Immunomodulatory Biomaterials for Cell Therapy and Tissue Engineering [electronic resource] : Recent Advancements / by Sudip Mukherjee, Boram Kim, Andrea Hernandez.
Material type:
TextSeries: Synthesis Lectures on Biomedical EngineeringPublisher: Cham : Springer Nature Switzerland : Imprint: Springer, 2024Edition: 1st ed. 2024Description: VI, 86 p. 27 illus., 25 illus. in color. online resourceContent type: - text
- computer
- online resource
- 9783031508448
- R856-857
Introduction -- Immunomodulation Strategies Using Biomaterial Chemistry and Physical Properties -- Use of Immunomodulatory Biomaterials in Diabetes Therapy -- Cell-based Therapies in Cancer -- Cell-based Therapies in Myocardial Infarction and Tissue Regeneration -- Conclusion.
This book presents the recent developments in immunomodulatory biomaterials for cell-based therapies in various diseases, including diabetes, cancer, cardiovascular disease, and bone regeneration. The authors first cover the fundamentals of conventional immunology and immunomodulation, before focusing on the history, advantages, and challenges of cell therapies. Biological cell therapy has gained immense attention for various diseases due to unique advantages it has over chemical drugs regarding cost, ease of production, toxicity, and therapeutic efficacy. However, these cell-based therapies need an inert delivery system that can locally deliver cells and minimally elicit foreign body response. The book discusses the foreign body response to the immunomodulatory biomaterials as well as the current and future strategies for potential mitigation of considerable immune responses toward immunomodulatory biomaterials and devices. In addition, this book: Presents the recent developments in immunomodulatory biomaterials for cell-based therapies in various diseases Discusses the history, advantages, and challenges of cell therapies as compared to conventional treatment Highlights future strategies for mitigation of immune responses toward immunomodulatory biomaterials and devices.
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