This book presents a multidisciplinary approach to digital transformation process of organizational transformation, offering support throughout the implementation process to all those interested. The digital transformation (DT) is a priority for many companies in the context of technological evolution. The use of appropriate tools, methodologies, methods, approaches, and techniques for DT, depending on the organizational characteristics, can contribute to a complete approach to organizational processes and to their efficiency. Digital transformation involves the adoption and use of new digital technologies to develop new products and services, modify existing ones and develop new business models to increase efficiency, productivity, and competitiveness. Starting from marketing to culture and education to health, automotive, engineering, mobility and human resources and others, it is addressed to professionals, practitioners, researchers, students, and other interested parties.