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Looking at Ribozymes Biology of Catalytic RNA [electronic resource] Benoît Masquida, Fabrice Leclerc

By:

Masquida, Benoît [aut]

Contributor(s):

Leclerc, Fabrice [aut]

Material type:

TextLanguage: English Publisher: Wiley 2024Edition: 1Description: 192ppContent type:

text

Media type:

computer

Carrier type:

online resource

ISBN:

9781394276639

Subject(s):

ribozymes; ribo-enzymes; catalytic RNA; intron; transfer RNAs; molecular biology; proteocentric; nucleocentric; genomes; functional diversity; catalytic mechanisms

Additional physical formats: Printed edition:: No title

Online resources:

Summary: Behind the neologism "ribozymes" lies a family of fascinating molecules, ribo-enzymes, which have been relatively little studied. These catalytically active RNAs are found in all strata of life, from viruses to the human genome. At the end of the 1970s, the discovery of a catalytic RNA nestled in an intron, followed by another involved in the maturation of transfer RNAs, led to the discovery of new ribozymes and the transition from a strictly "proteocentric" vision, inherited from the dogma of molecular biology, to a more "nucleocentric" one. Since then, a variety of ribozymes have been identified in genomes, where their functions often remain mysterious. Looking at Ribozymes traces the discovery of these molecules and presents a picture of their functional diversity, catalytic mechanisms and distribution within the tree of life.

Item type: List(s) this item appears in: Titluri cărți electronice Wiley 2025 (444 titluri)

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Behind the neologism "ribozymes" lies a family of fascinating molecules, ribo-enzymes, which have been relatively little studied. These catalytically active RNAs are found in all strata of life, from viruses to the human genome. At the end of the 1970s, the discovery of a catalytic RNA nestled in an intron, followed by another involved in the maturation of transfer RNAs, led to the discovery of new ribozymes and the transition from a strictly "proteocentric" vision, inherited from the dogma of molecular biology, to a more "nucleocentric" one. Since then, a variety of ribozymes have been identified in genomes, where their functions often remain mysterious. Looking at Ribozymes traces the discovery of these molecules and presents a picture of their functional diversity, catalytic mechanisms and distribution within the tree of life.

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