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RNA as a Drug Target (Record no. 67083)

MARC details
000 -LEADER
fixed length control field	03548nam a22004574u 4500
001 - CONTROL NUMBER
control field	10.1002/9783527840458
003 - CONTROL NUMBER IDENTIFIER
control field	Wiley
005 - DATE AND TIME OF LATEST TRANSACTION
control field	20251030120311.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field	cr nn 008mam\|a
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field	240705t2024\|\|\|\|xxu fs\| \|0\|\| 0\|eng\|\|
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number	9783527840458
Qualifying information	electronic
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code	10.1002/9783527840458
Source of number or code	doi
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title	eng
245 00 - TITLE STATEMENT
Title	RNA as a Drug Target
Remainder of title	The Next Frontier for Medicinal Chemistry
Medium	[electronic resource]
Statement of responsibility, etc.	Edited by John Schneekloth, Martin Pettersson, Raimund Mannhold, Helmut Buschmann, Jörg Holenz.
250 ## - EDITION STATEMENT
Edition statement	1
260 ## - Date publicare
Name of publisher, distributor, etc.	Wiley
Date of publication, distribution, etc.	2024
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Name of producer, publisher, distributor, manufacturer	Wiley
Date of production, publication, distribution, manufacture, or copyright notice	2024
300 ## - PHYSICAL DESCRIPTION
Extent	416pp.;
336 ## - CONTENT TYPE
Content type term	text
Content type code	txt
Source	rdacontent
337 ## - MEDIA TYPE
Media type term	computer
Media type code	c
Source	rdamedia
338 ## - CARRIER TYPE
Carrier type term	online resource
Carrier type code	cr
Source	rdacarrier
347 ## - DIGITAL FILE CHARACTERISTICS
File type	text file
Source	rdaft
347 ## - DIGITAL FILE CHARACTERISTICS
Encoding format	PDF
490 1# - SERIES STATEMENT
Series statement	Methods and Principles in Medicinal Chemistry
520 ## - SUMMARY, ETC.
Summary, etc.	Discover a new paradigm in drug discovery that greatly expands the space of addressable drug targets and potential novel drugs Existing paradigms for drug discovery have focused largely on enzymes and other proteins as drug targets. In recent years, however, different varieties of ribonucleic acids have emerged as a viable focus for target-based drug discovery, with the potential to revolutionize the strategy and approach for this essential step in the drug development process. RNA as a Drug Target: The Next Frontier for Medicinal Chemistry offers a practice-oriented introduction to developing drug-like small molecules that selectively modulate both coding and non-coding RNAs. Beginning with a description and characterization of existing druggable RNAs, the book discusses how to approach different RNA targets for drug discovery. The result is a crucial resource for targeting RNAs and creating the next generation of life-saving pharmaceuticals. RNA as a Drug Target readers will also find: A complete "toolbox" for working with RNA, from structure determination to screening and lead generation techniques A wide range of addressable targets and mechanisms, including splicing modulation, riboswitches, targeted degradation, and more Authoritative discussion of the potential of RNA-targeted small molecule therapeutics for drugging the epitranscriptome RNA as a Drug Target provides an expert introduction to a new frontier in pharmaceutical research for medicinal chemists, biochemists, molecular biologists, and members of the pharmaceutical industry.
650 #4 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element
9 (RLIN)	91621
650 #4 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element
9 (RLIN)	65465
650 #4 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element
9 (RLIN)	91323
653 00 - INDEX TERM--UNCONTROLLED
Uncontrolled term	Proteins; regulatory RNA; drug developer; undruggable disease; ribonucleic acid; enzyme; receptor; drug target; new therapeutics; medical chemist; biochemist; molecular biologist; pharmaceutical industry
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name	Schneekloth, John
Relator code	edt
9 (RLIN)	91773
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name	Pettersson, Martin
Relator code	edt
9 (RLIN)	91774
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name	Mannhold, Raimund
Relator code	edt
9 (RLIN)	91775
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name	Buschmann, Helmut
Relator code	edt
9 (RLIN)	91776
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name	Holenz, Jörg
Relator code	edt
9 (RLIN)	91777
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Relationship information	Printed edition:
International Standard Book Number	9783527351008
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE
Uniform title	Methods and Principles in Medicinal Chemistry
9 (RLIN)	91626
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier	<a href="https://doi.org/10.1002/9783527840458">https://doi.org/10.1002/9783527840458</a>
Host name	Wiley Online Library
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier	<a href="https://onlinelibrary.wiley.com/action/showBook?doi=10.1002%2F9783527840458">https://onlinelibrary.wiley.com/action/showBook?doi=10.1002%2F9783527840458</a>
Host name	Wiley Online Library
856 42 - ELECTRONIC LOCATION AND ACCESS
Materials specified	Cover Image
Uniform Resource Identifier	<a href="https://onlinelibrary.wiley.com/cms/asset/d9f541f8-0390-4132-86af-33a205ae917d/9783527840458.cover.gif">https://onlinelibrary.wiley.com/cms/asset/d9f541f8-0390-4132-86af-33a205ae917d/9783527840458.cover.gif</a>
Host name	Wiley Online Library

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