Physics of cancer. (Record no. 68367)
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| 001 - CONTROL NUMBER | |
| control field | 9780750340038 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | IOP |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20251030124213.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS | |
| fixed length control field | m eo d |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
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| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 231201s2023 enka fob 000 0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9780750340038 |
| Qualifying information | ebook |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9780750340021 |
| Qualifying information | mobi |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Canceled/invalid ISBN | 9780750340014 |
| Qualifying information | |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Canceled/invalid ISBN | 9780750340045 |
| Qualifying information | myPrint |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1088/978-0-7503-4003-8 |
| Source of number or code | doi |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (CaBNVSL)thg00083689 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (OCoLC)1412322821 |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | CaBNVSL |
| Language of cataloging | eng |
| Description conventions | rda |
| Transcribing agency | CaBNVSL |
| Modifying agency | CaBNVSL |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RC262 |
| Item number | .M547 2023eb vol. 4 |
| 060 #4 - NATIONAL LIBRARY OF MEDICINE CALL NUMBER | |
| Classification number | QZ 203 |
| Item number | M632p 2023eb vol. 4 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | PHVN |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | SCI009000 |
| Source | bisacsh |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Mierke, Claudia Tanja, |
| Relator term | author. |
| 9 (RLIN) | 96509 |
| 245 10 - TITLE STATEMENT | |
| Title | Physics of cancer. |
| Number of part/section of a work | Volume 4, |
| Name of part/section of a work | Mechanical characterization of cells / |
| Statement of responsibility, etc. | Claudia Tanja Mierke. |
| 246 30 - VARYING FORM OF TITLE | |
| Title proper/short title | Mechanical characterization of cells. |
| 250 ## - EDITION STATEMENT | |
| Edition statement | Second edition. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | Bristol [England] (Temple Circus, Temple Way, Bristol BS1 6HG, UK) : |
| Name of producer, publisher, distributor, manufacturer | IOP Publishing, |
| Date of production, publication, distribution, manufacture, or copyright notice | [2023] |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 online resource (various pagings) : |
| Other physical details | illustrations (some color). |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media type term | electronic |
| Source | isbdmedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | online resource |
| Source | rdacarrier |
| 490 1# - SERIES STATEMENT | |
| Series statement | [IOP release $release] |
| 490 1# - SERIES STATEMENT | |
| Series statement | Biophysical Society-IOP series |
| 490 1# - SERIES STATEMENT | |
| Series statement | IOP ebooks. [2023 collection] |
| 500 ## - GENERAL NOTE | |
| General note | "Version: 20231101"--Title page verso. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc | Includes bibliographical references. |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 1. Mechanosensing and the mechanotransduction of cells -- 1.1. An introduction to mechanosensation and mechanotransduction in living cells -- 1.2. Molecular mechanosensory behavior -- 1.3. The role of focal adhesion proteins -- 1.4. Interplay between mechanosensors -- 1.5. The interplay between focal adhesion proteins and cell-matrix receptors -- 1.6. The interplay between focal adhesion proteins and cell-cell adherence junctions -- 1.7. Force detection and transduction at adherens junctions -- 1.8. The transfer of mechanical forces at the cadherin-catenin complex -- 1.9. The role of the cytoskeleton -- 1.10. The role of the nucleus in sensing mechanical cues -- 1.11. Restrained mechanosensing in cancer -- 1.12. The regulation of gene expression in mechanotransduction in cancer cells -- 1.13. Alterations of the extracellular matrix environment in cancerous diseases -- 1.14. Conclusions and future perspectives |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 2. Overview and discussion of biophysical techniques for the mechanical characterization of cell nuclei and cells -- 2.1. Introduction to biophysical techniques used for the mechanical characterization of the nuclei of living cells -- 2.2. Analysis of nuclear positioning in a living cell -- 2.3. Analysis of the nuclear mechanical characteristics -- 2.4. Components of the nuclear framework contribute to mechanosensing -- 2.5. Analyses of nuclear mechanics -- 2.6. Analysis of the cytoskeleton and cell cortex -- 2.7. A critical discussion of mechanical measurements of living cells -- 2.8. A discussion of the selection of a specific biophysical technique -- 2.9. Conclusions and future research |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 3. Overview and discussion of biophysical techniques for the mechanical characterization of plasma membranes -- 3.1. A concise introduction to plasma membrane models -- 3.2. Giant plasma membrane vesicles serve as a model for the plasma membrane -- 3.3. Biophysical analysis of the plasma membrane of cells -- 3.4. The principles of the dynamics of the plasma membrane -- 3.5. Models and theories of the plasma membrane -- 3.6. The heat theory of the plasma membrane -- 3.7. The phenomenon of bioelectricity -- 3.8. The main findings in cancer research related to the plasma membrane -- 3.9. The prominent role of the bioelectrical code -- 3.10. Are aging and cancer opposite or the same sides of the coin in terms of pathology? -- 3.11. Bioelectric signal transmission within the mechanical microenvironment -- 3.12. Deciphering the direction of the flow of communication : separating the mechanical microenvironment from the bioelectrical signaling -- 3.13. Conclusions and future research |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 4. A survey of biophysical techniques used for the mechanical characterization of cell spheroids, organoids, and tumoroids -- 4.1. An overview of multicellular culture models -- 4.2. Tissue explants -- 4.3. Cell cluster formation and cell aggregates -- 4.4. Cell spheroids -- 4.5. Organoids -- 4.6. The effect of organoid vascularization -- 4.7. Tumoroids -- 4.8. Mechanical measurements of cell clusters, spheroids, organoids, or tumoroids -- 4.9. The effects of cell sorting and invasion -- 4.10. A discussion of the advantages and disadvantages of cell aggregate mechanical analyses -- 4.11. Conclusions and future research. |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | This is the fourth volume of the highly regarded Physics of Cancer (Second Edition) series, written with the aim of making very important topics in the physics of cancer visible to the research community. This fourth volume deals with mechanobiology using biophysical methods. The first chapter deals with mechanosensing and mechanotransduction on vastly different length scales. The second chapter discusses biophysical techniques for mechanical phenotype characterization of cells and nuclei. The third provides an overview of the mechanical phenotype of the plasma membrane. The fourth chapter contains the latest insights into the mechanical assessment of cell spheroids, organoids and tumoroids. The basic approach of this text is to present the latest promising findings to the scientific community, addressing scientists at all career stages. Part of Biophysical Society-IOP series. |
| 521 ## - TARGET AUDIENCE NOTE | |
| Target audience note | Scientists, researchers, graduate students, instructors in biophysics. |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Also available in print. |
| 538 ## - SYSTEM DETAILS NOTE | |
| System details note | Mode of access: World Wide Web. |
| 538 ## - SYSTEM DETAILS NOTE | |
| System details note | System requirements: Adobe Acrobat Reader, EPUB reader, or Kindle reader. |
| 545 ## - BIOGRAPHICAL OR HISTORICAL DATA | |
| Biographical or historical data | Claudia Tanja Mierke is Head of the Department of Biological Physics at the Peter Debye Institute for Soft Matter Physics at Leipzig University. Her primary research areas are cell biophysics and cell mechanics, adhesion, motility (invasion) in biomimetic matrices, cancer and inflammation, cancer metastasis and tumor microenvironment mechanics. She has published over 150 refereed journal articles, books and book chapters largely dealing with soft matter physics and the physics of cancer. Over the past 18 years, Claudia had taught courses in biophysics, soft matter physics, cell biology for physicists and cellular biophysics, to both undergraduate and graduate students. |
| 588 0# - SOURCE OF DESCRIPTION NOTE | |
| Source of description note | Title from PDF title page (viewed on December 1, 2023). |
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| 9 (RLIN) | 66239 |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
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| 9 (RLIN) | 66239 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
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| Source of heading or term | bicssc |
| 9 (RLIN) | 66239 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | |
| Source of heading or term | bisacsh |
| 9 (RLIN) | 95352 |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | |
| General subdivision | Mechanical properties. |
| 9 (RLIN) | 96516 |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | |
| 9 (RLIN) | 4311 |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | Institute of Physics (Great Britain), |
| Relator term | publisher. |
| 9 (RLIN) | 17702 |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Print version: |
| International Standard Book Number | 9780750340014 |
| -- | 9780750340045 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | IOP (Series). |
| Name of part/section of a work | Release 23. |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Biophysical Society-IOP series. |
| 9 (RLIN) | 96362 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | IOP ebooks. |
| Name of part/section of a work | 2023 collection. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://iopscience.iop.org/book/mono/978-0-7503-4003-8">https://iopscience.iop.org/book/mono/978-0-7503-4003-8</a> |
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