TY  - BOOK
AU  - Mukherjee,Sudip
AU  - Kim,Boram
AU  - Hernandez,Andrea
ED  - SpringerLink (Online service)
TI  - Immunomodulatory Biomaterials for Cell Therapy and Tissue Engineering: Recent Advancements 
T2  - Synthesis Lectures on Biomedical Engineering,
SN  - 9783031508448
AV  - R856-857 
PY  - 2024///
CY  - Cham
PB  - Springer Nature Switzerland, Imprint: Springer
KW  - Biomedical engineering
KW  - Biomaterials
KW  - Medicine
KW  - Research
KW  - Biology
KW  - Therapeutics
KW  - Biomedical Engineering and Bioengineering
KW  - Biomedical Materials
KW  - Biomedical Research
KW  - Biomedical Devices and Instrumentation
N1  - Introduction -- Immunomodulation Strategies Using Biomaterial Chemistry and Physical Properties -- Use of Immunomodulatory Biomaterials in Diabetes Therapy -- Cell-based Therapies in Cancer -- Cell-based Therapies in Myocardial Infarction and Tissue Regeneration -- Conclusion
N2  - This book presents the recent developments in immunomodulatory biomaterials for cell-based therapies in various diseases, including diabetes, cancer, cardiovascular disease, and bone regeneration. The authors first cover the fundamentals of conventional immunology and immunomodulation, before focusing on the history, advantages, and challenges of cell therapies. Biological cell therapy has gained immense attention for various diseases due to unique advantages it has over chemical drugs regarding cost, ease of production, toxicity, and therapeutic efficacy. However, these cell-based therapies need an inert delivery system that can locally deliver cells and minimally elicit foreign body response. The book discusses the foreign body response to the immunomodulatory biomaterials as well as the current and future strategies for potential mitigation of considerable immune responses toward immunomodulatory biomaterials and devices. In addition, this book: Presents the recent developments in immunomodulatory biomaterials for cell-based therapies in various diseases Discusses the history, advantages, and challenges of cell therapies as compared to conventional treatment Highlights future strategies for mitigation of immune responses toward immunomodulatory biomaterials and devices
UR  - https://doi.org/10.1007/978-3-031-50844-8
ER  -