03778nam a22005655i 4500001001800000003000900018005001700027007001500044008004100059020003700100024003500137050001300172072001600185072002300201072001500224100008600239245017200325250001800497264006900515300006300584336002600647337002600673338003600699347002400735490006100759505028200820520129801102650002802400650001802428650003102446650003002477650002502507650004702532650003302579650001802612650003202630650004402662650002502706700008002731700008702811710003402898773002602932776003602958776003602994776003603030830006803066856004603134912001503180999001703195978-3-031-50844-8DE-He21320251030111406.0cr nn 008mamaa240129s2024    sz |    s    |||| 0|eng d  a97830315084489978-3-031-50844-87 a10.1007/978-3-031-50844-82doi 4aR856-857 7aMQW2bicssc 7aTEC0590002bisacsh 7aMQW2thema1 aMukherjee, Sudip.eauthor.4aut4http://id.loc.gov/vocabulary/relators/aut97008610aImmunomodulatory Biomaterials for Cell Therapy and Tissue Engineeringh[electronic resource] :bRecent Advancements /cby Sudip Mukherjee, Boram Kim, Andrea Hernandez.  a1st ed. 2024. 1aCham :bSpringer Nature Switzerland :bImprint: Springer,c2024.  aVI, 86 p. 27 illus., 25 illus. in color.bonline resource.  atextbtxt2rdacontent  acomputerbc2rdamedia  aonline resourcebcr2rdacarrier  atext filebPDF2rda1 aSynthesis Lectures on Biomedical Engineering,x1930-03360 aIntroduction -- Immunomodulation Strategies Using Biomaterial Chemistry and Physical Properties -- Use of Immunomodulatory Biomaterials in Diabetes Therapy -- Cell-based Therapies in Cancer -- Cell-based Therapies in Myocardial Infarction and Tissue Regeneration -- Conclusion.  aThis book presents the recent developments in immunomodulatory biomaterials for cell-based therapies in various diseases, including diabetes, cancer, cardiovascular disease, and bone regeneration. The authors first cover the fundamentals of conventional immunology and immunomodulation, before focusing on the history, advantages, and challenges of cell therapies. Biological cell therapy has gained immense attention for various diseases due to unique advantages it has over chemical drugs regarding cost, ease of production, toxicity, and therapeutic efficacy. However, these cell-based therapies need an inert delivery system that can locally deliver cells and minimally elicit foreign body response. The book discusses the foreign body response to the immunomodulatory biomaterials as well as the current and future strategies for potential mitigation of considerable immune responses toward immunomodulatory biomaterials and devices. In addition, this book: Presents the recent developments in immunomodulatory biomaterials for cell-based therapies in various diseases Discusses the history, advantages, and challenges of cell therapies as compared to conventional treatment Highlights future strategies for mitigation of immune responses toward immunomodulatory biomaterials and devices. 0aBiomedical engineering. 0aBiomaterials. 0aMedicinexResearch.962598 0aBiologyxResearch.965629 0aTherapeutics.97008714aBiomedical Engineering and Bioengineering.24aBiomedical Materials.96392224aBiomaterials.24aBiomedical Research.96563324aBiomedical Devices and Instrumentation.24aTherapeutics.9700871 aKim, Boram.eauthor.4aut4http://id.loc.gov/vocabulary/relators/aut9700881 aHernandez, Andrea.eauthor.4aut4http://id.loc.gov/vocabulary/relators/aut9700892 aSpringerLink (Online service)0 tSpringer Nature eBook08iPrinted edition:z978303150843108iPrinted edition:z978303150845508iPrinted edition:z9783031508462 0aSynthesis Lectures on Biomedical Engineering,x1930-033697009040uhttps://doi.org/10.1007/978-3-031-50844-8  aZDB-2-SXSC  c57354d57354