02943nam a22004575i 4500001001800000003000900018005001700027007001500044008004100059020001800100024003500118050001200153072001600165072002300181072001500204245010300219250001800322264007500340300006400415336002600479337002600505338003600531347002400567505036700591520100400958650002701962650002701989650002802016650001802044650001902062650005002081650004702131650001802178700007502196710003402271773002602305776003602331776003602367776003602403856004602439978-3-031-55653-1DE-He21320251030111748.0cr nn 008mamaa240327s2024    sz |    s    |||| 0|eng d  a97830315565317 a10.1007/978-3-031-55653-12doi 4aRS199.5 7aTCB2bicssc 7aSCI0100002bisacsh 7aTCB2thema10aDrug Delivery Systems for Musculoskeletal Tissuesh[electronic resource] /cedited by Sumit Murab.  a1st ed. 2024. 1aCham :bSpringer International Publishing :bImprint: Springer,c2024.  aIX, 220 p. 51 illus., 43 illus. in color.bonline resource.  atextbtxt2rdacontent  acomputerbc2rdamedia  aonline resourcebcr2rdacarrier  atext filebPDF2rda0 aIntroduction to Musculoskeletal Tissues & Drug Delivery Systems -- Drug Delivery Systems for Bone -- Drug Delivery Systems for Cartilage -- Drug Delivery Systems for Intervertebral Disc -- Drug Delivery Systems for Tendon and Ligament -- Drug Delivery Systems for Muscles -- Challenges in Clinical Translation of Musculoskeletal Drug Delivery Systems -- Index. .  aMusculoskeletal tissues are hard to heal if damaged by disease or trauma. If damaged, they cause pain and hinder regular movements of our bodies. Drug delivery systems that can be used for healing and regenerating these tissues need to be specialized to bear physiological loading on these tissues while helping in controlled release of drug or biomolecules for healing the tissue. This book discusses the pathology of orthopaedic diseases and the requirements of local drug delivery platforms that can help in the treatment of the pathology as well as regeneration of the tissue. The book also discusses in detail the mechanical properties and support that these systems provide to the damaged musculoskeletal tissues and how long-term healing and regeneration is possible. This is an ideal book for students, postdoctoral fellows and faculty at academic universities, and industry professionals who are working on drug delivery, orthopaedic diseases, tissue engineering, and regenerative medicine. 0aDrug delivery systems. 0aRegenerative medicine. 0aBiomedical engineering. 0aBiomaterials.14aDrug Delivery.24aRegenerative Medicine and Tissue Engineering.24aBiomedical Engineering and Bioengineering.24aBiomaterials.1 aMurab, Sumit.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt2 aSpringerLink (Online service)0 tSpringer Nature eBook08iPrinted edition:z978303155652408iPrinted edition:z978303155654808iPrinted edition:z978303155655540uhttps://doi.org/10.1007/978-3-031-55653-1