04007nam a22005655i 4500 978-981-99-8994-2 DE-He213 20251030111751.0 cr nn 008mamaa 240328s2024 si | s |||| 0|eng d 9789819989942 978-981-99-8994-2 10.1007/978-981-99-8994-2 doi QD551-578 PNRH bicssc SCI013050 bisacsh PNRH thema Go, Su Yong. author. aut http://id.loc.gov/vocabulary/relators/aut 74201 Photochemical and Electrochemical Activation Strategies of C(sp3)-Based Building Blocks for Organic Synthesis [electronic resource] / by Su Yong Go. 1st ed. 2024. Singapore : Springer Nature Singapore : Imprint: Springer, 2024. XXVII, 169 p. 257 illus., 166 illus. in color. online resource. text txt rdacontent computer c rdamedia online resource cr rdacarrier text file PDF rda Springer Theses, Recognizing Outstanding Ph.D. Research, 2190-5061 Part I. C(sp2)-C(sp3) Bond Formation Reactions Enabled by Photoredox/Nickel Dual Catalysis -- Chapter 1. The Key Concepts and Strategy in Photoredox/Nickel Dual Catalysis and Application to C-C Bond Formation Reactions -- Chapter 2. Highl Regioselective and E/Z Selective Hydroalkylation of Alkyne via Photoredox Mediated Ni/Ir Dual Catalysis -- Part II. Development of C(sp3)-Heteroatom Bond-Forming Reactions via Electrochemical Activation of C(sp3)-B Bonds and Follow-up Projects -- Chapter 3. Recent Achievements of C(sp3)-Heteroatom Bond Formation in Electroorganic Synthesis and History of C(sp3)-B Bond Activation -- Chapter 4. Introduction of Heteroatoms to Alkyl Carbocations Generated from Alkylboron Reagents via Electrochemical Activation -- Chapter 5. Functionalization of Alkylboron Compounds Under Other Reaction Conditions. This book addresses novel C(sp3)-C(sp2) and C(sp3)-heteroatom bond-forming reactions. Two strategies are given in the book using photoredox or electrochemical methods. The first strategy describes that the hydroalkylation of alkynes via photoredox-mediated Ni/Ir dual catalysis produces trisubstituted alkenes as versatile synthetic building blocks for the synthesis of pharmaceutical agents and natural products. High regioselectivity and E/Z-selectivity were achieved by introducing silyl groups that can provide steric and electronic effects to these selectivities with extensive opportunities for post-functionalization. The second strategy enables the development of C(sp3)-heteroatom bond-forming reactions through the electrochemical activation of C(sp3)-B bonds. The bonding of heteroatoms to carbon atoms has been an enduring subject of investigation for organic chemists. The function of most molecules is mainly determined by heteroatoms attached to the carbon atom, although the backbone structure of organic compounds comprises carbon fragments. Electrochemistry. 65005 Photochemistry. 74202 Catalysts. 74203 Catalysis. 66843 Materials. Electrochemistry. 65005 Photochemistry. 74202 Catalyst Synthesis. 74204 Catalytic Materials. 67785 SpringerLink (Online service) Springer Nature eBook Printed edition: 9789819989935 Printed edition: 9789819989959 Springer Theses, Recognizing Outstanding Ph.D. Research, 2190-5061 66370 https://doi.org/10.1007/978-981-99-8994-2 ZDB-2-CMS ZDB-2-SXC 58745 58745