04198nam a22005655i 4500001001800000003000900018005001700027007001500044008004100059020003700100024003500137050000700172072001600179072002300195072001500218245018300233250001800416264007200434300006500506336002600571337002600597338003600623347002400659505119700683520083601880650001802716650002302734650002102757650002602778650002502804650001802829650002302847650002502870650002502895650002502920700008402945700008403029700008203113700009303195700008503288710003403373773002603407776003603433776003603469776003603505856004603541912001403587912001403601999001703615978-981-99-8373-5DE-He21320251030111757.0cr nn 008mamaa240330s2024    si |    s    |||| 0|eng d  a97898199837359978-981-99-8373-57 a10.1007/978-981-99-8373-52doi 4aQR 7aPSG2bicssc 7aSCI0450002bisacsh 7aPSG2thema10aExosomes Based Drug Delivery Strategies for Brain Disordersh[electronic resource] /cedited by Neeraj Mishra, Sumel Ashique, Ashish Garg, Vadivalagan Chithravel, Krishnan Anand.  a1st ed. 2024. 1aSingapore :bSpringer Nature Singapore :bImprint: Springer,c2024.  aXVI, 451 p. 55 illus., 53 illus. in color.bonline resource.  atextbtxt2rdacontent  acomputerbc2rdamedia  aonline resourcebcr2rdacarrier  atext filebPDF2rda0 aChapter 1_ Introduction to Exosome and its role in Brain disorders -- Chapter 2_ Exosomes: Biogenesis, Composition and Synthesis -- Chapter 3_ Therapeutic Impact of Exosomes in Stroke and Transient Ischemic Attack (TIA) -- Chapter 4_ Role of exosomes in Multiple Sclerosis -- Chapter 5_ Therapeutic impact of exosomes Stroke and Transient Ischemic Attack (TIA) -- Chapter 6_ Role of exosomes in Parkinson’s and Alzheimer’s diseases -- Chapter 7_ Role of exosomes in Epilepsy and other Seizure Disorders -- Chapter 8_ Role of exosomes in management of depression -- Chapter 9_ Role of Microbiota-Derived Exosomes in Gut-Brain Communication for the treatment of brain disorders -- Chapter 10_ Advancement of Engineered Exosomes to deliver therapeutic protein cargos in brain disorders -- Chapter 11_ Correlation between exosomes and neuro inflammation in various brain disorders -- Chapter 12_ Recent challenges of exosomes as novel carrier in various brain disorders -- Chapter 13_Advancement of radiolabeled exosomes in brain disorders -- Chapter 14_ Exosomes as future diagnostic tool for brain disorders -- Chapter 15_ Toxicity studies of exosomes and the potential overcome approaches.  aThis book provides a comprehensive overview of the role of exosomes in brain diseases, including stroke, multiple sclerosis, Parkinson's disease, Alzheimer's disease, epilepsy, and depression. It covers the basics of exosome biogenesis, composition, and synthesis, as well as the therapeutic potential of exosomes in brain disorders. The correlation between exosomes and neuroinflammation, the challenges of using exosomes as a novel carrier, and engineered exosomes to deliver therapeutic protein are covered well in this book. Use of radiolabelled exosomes as a diagnostic tool and the toxicity studies of exosomes with potential overcome approaches. It is an essential resource for researchers, clinicians, and healthcare professionals working in the field of exosome research, especially on its applications in brain disorders. 0aMicrobiology. 0aMolecular biology. 0aCytology.967436 0aNeurosciences.968384 0aPharmacology.96784414aMicrobiology.24aMolecular Biology.24aCell Biology.96744024aNeuroscience.96838624aPharmacology.9678441 aMishra, Neeraj.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt9744631 aAshique, Sumel.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt9744641 aGarg, Ashish.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt9744651 aChithravel, Vadivalagan.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt9744661 aAnand, Krishnan.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt9744672 aSpringerLink (Online service)0 tSpringer Nature eBook08iPrinted edition:z978981998372808iPrinted edition:z978981998374208iPrinted edition:z978981998375940uhttps://doi.org/10.1007/978-981-99-8373-5  aZDB-2-SME  aZDB-2-SXM  c58838d58838