04798nam a22005655i 4500 978-981-99-8365-0 DE-He213 20251030111804.0 cr nn 008mamaa 240403s2024 si | s |||| 0|eng d 9789819983650 978-981-99-8365-0 10.1007/978-981-99-8365-0 doi R850.A1-854 QH315-320 MBGR bicssc MED106000 bisacsh MBGR thema Extracellular Vesicles [electronic resource] : From Bench to Bedside / edited by Qian Wang, Lei Zheng. 1st ed. 2024. Singapore : Springer Nature Singapore : Imprint: Springer, 2024. XXII, 588 p. 77 illus., 70 illus. in color. online resource. text txt rdacontent computer c rdamedia online resource cr rdacarrier text file PDF rda Section 1 EVs biology and function -- Classification and nomenclature of extracellular vesicles -- EVs biogenesis and function -- The mechanism of interaction between extracellular vesicles and target cells -- Biological functions of EVs in various systems -- The role and mechanism of EVs in the process of disease -- Section 2 Technologies and methods for EVs research -- Methods for EV isolation, purification and characterization -- Technologies for the analysis of EV omics -- Flow cytometry for single EV analysis -- Microfluidics-based technologies for EVs research -- Biosensing Technologies for EVs detection -- Technology for EVs surface functionalization -- Technologies for visualization and tracking of EVs -- Methods for EVs function research -- Chemical Biology Investigation of Extracellular Vesicles -- Section 3 EVs biomarker in diseases -- EV biomarker screening and clinical verification -- EVs biomarker for cancer -- EVs biomarker for disease diagnosis -- EVs biomarker for immune disorder -- EVs biomarker for neurological diseases -- EVs biomarker for infectious disease -- EVs biomarker for renal diseases -- EVs biomarker for thrombosis -- Section 4 EVs for disease therapy and prevention -- Stem cell-derived EVs for disease therapy -- EVs in cancer immunotherapy -- Platelet-derived EVs in disease therapy -- Plant-derived Extracellular Nanovesicles for Disease Therapy -- EVs engineering for therapy -- Other EVs for disease therapy -- EV-based clinical trial -- Section 5 Introduction to the guidelines and resources for EV research -- Introduction to the guidelines for EV research -- Introduction to online nucleic acid database for EV research -- Introduction of systems biology in EV. This book aims to provide a comprehensive and systematic understanding of research on extracellular vesicles (EVs). Extracellular vesicles, including exosomes and microvesicles, are nano-sized lipid bilayer encapsulated membranes carrying proteins, lipids, nucleic acids. They are shed by the majority of the cells into the extracellular milieu and present in many biological fluids (blood, urine, saliva, breast milk, cerebrospinal fluid, follicular fluid, semen, lung lavage, and tears). With numerous research publications in recent years, the study of EVs is the emerging field across plenty of disciplines. Many researches and efforts have shown their biogenesis, multiple roles in physiological and pathophysiological processes, and their potential roles as therapeutic agents. The book is organized by outstanding scientists in EV field from the Chinese Society for Extracellular Vesicle (CSEV). It covers the biological basic research of EVs, especially on technologies and methods, as well as the clinical application of EVs as biomarkers for disease diagnosis and therapy. Medicine Research. 62598 Biology Research. 65629 Cytology. 67436 Biological transport. 74718 Cell membranes. 74719 Translational Research. 70704 Cell Biology. 67440 Membrane Trafficking. 74720 Wang, Qian. editor. edt http://id.loc.gov/vocabulary/relators/edt 74721 Zheng, Lei. editor. edt http://id.loc.gov/vocabulary/relators/edt 69550 SpringerLink (Online service) Springer Nature eBook Printed edition: 9789819983643 Printed edition: 9789819983667 Printed edition: 9789819983674 https://doi.org/10.1007/978-981-99-8365-0 ZDB-2-SME ZDB-2-SXM 58940 58940