03469nam a22005415i 4500001001800000003000900018005001700027007001500044008004100059020003700100024003500137050001300172050001300185072001500198072001500213072002300228072001400251072001400265245016500279250001800444264007500462300006600537336002600603337002600629338003600655347002400691505061200715520101001327650002302337650002002360650002402380650002002404650002302424650002002447650002202467650002302489650002002512700009002532700008202622710003402704773002602738776003602764776003602800856004602836912001402882912001402896999001702910978-3-031-53858-2DE-He21320251030111806.0cr nn 008mamaa240405s2024    sz |    s    |||| 0|eng d  a97830315385829978-3-031-53858-27 a10.1007/978-3-031-53858-22doi 4aRC1-1245 4aRC1-1245 7aMJ2bicssc 7aMJ2bicssc 7aMED0450002bisacsh 7aMJ2thema 7aMJ2thema10aVon Hippel-Lindau Diseaseh[electronic resource] :bA Comprehensive Guide to Diagnosis, Treatment, and Management /cedited by Dhaval Thakor Patel, Amit Tirosh.  a1st ed. 2024. 1aCham :bSpringer International Publishing :bImprint: Springer,c2024.  aVIII, 252 p. 32 illus., 24 illus. in color.bonline resource.  atextbtxt2rdacontent  acomputerbc2rdamedia  aonline resourcebcr2rdacarrier  atext filebPDF2rda0 aDr. Von Hippel, Dr. Lindau and the History of VHL Disease -- VHL Gene and the Molecular Pathophysiology of VHL -- Epidemiology of the VHL Disease -- Hemangioblastomas of Brain and Spine -- Retinal Hemangioblastomas -- Clear-cell Renal Cell Carcinoma -- Endolymphatic Sac Tumors -- Pheochromocytomas -- Pancreatic Manifestations of VHL -- Anatomical and Functional Imaging in VHL -- Advanced Disease-Medical Interventions -- Current Clinical Trials, and Future Research Perspectives -- Suggested Guidelines for the Screening, Surveillance and Management of VHL Manifestations -- Psychological Aspects of VHL.  aVon Hippel-Lindau (VHL) disease is an inherited disorder characterized by the abnormal growth of both benign and cancerous tumors and cysts in many parts of the body. Considering the number of manifestations of the VHL disease, screening and management is complex and requires a multidisciplinary effort as well as an understanding of the interplay between all the manifestations. This book is one of the first to provide fundamental knowledge about VHL and the know-how on the various manifestations of this complex syndrome. Various aspects of VHL are reflected in this book's table of contents, written by the leading experts in each field discussed. Comprehensive and easy-to-use, this book offers a detailed and comprehensive analysis of the manifestations and management of patients with VHL and serves as the definitive book on the management of patients with VHL for surgical oncologists, endocrinologists, urologists, neurosurgeons, ophthalmologist, radiologists, and all primary care physicians. 0aInternal medicine. 0aSurgery.972080 0aNeurology .966816 0aUrology.96954914aInternal Medicine.24aSurgery.97208024aNeurology.96681624aInternal Medicine.24aUrology.9695491 aPatel, Dhaval Thakor.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt9747721 aTirosh, Amit.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt9747732 aSpringerLink (Online service)0 tSpringer Nature eBook08iPrinted edition:z978303153857508iPrinted edition:z978303153859940uhttps://doi.org/10.1007/978-3-031-53858-2  aZDB-2-SME  aZDB-2-SXM  c58968d58968