03430nam a22005295i 4500 978-3-031-41777-1 DE-He213 20251030111810.0 cr nn 008mamaa 240409s2024 sz | s |||| 0|eng d 9783031417771 978-3-031-41777-1 10.1007/978-3-031-41777-1 doi RC346-429.2 MJN bicssc MED056000 bisacsh MKJ thema Stroke Genetics [electronic resource] / edited by Pankaj Sharma, James F. Meschia. 3rd ed. 2024. Cham : Springer International Publishing : Imprint: Springer, 2024. XII, 624 p. 50 illus., 32 illus. in color. online resource. text txt rdacontent computer c rdamedia online resource cr rdacarrier text file PDF rda Introduction -- Familial stroke epidemiology -- Association study results -- GWAS -- Aneurysms/carvernous/AVM -- ICH/amyloid/microbleeds -- CADASIL -- Fabry -- MELAS -- Sickle -- Other monogenic -- White matter disease -- Carotid atherosclerosis -- Dissection -- Pharmacogenomics -- Non-Caucasian stroke genetics -- Small vessel disease -- Genetics of neuroimaging in stroke -- Cerebrovenous thrombosis -- Ethics. This revised, expanded third edition updates the reader on this fast moving field as well providing an overall understanding of the genetics of complex diseases by using stroke as a paradigm. The reader will gain a comprehensive understanding of cerebrovascular genetics including the epidemiological evidence for the genetic basis of ischemic and hemorrhagic stroke, knowledge of its molecular basis from association, linkage and recent genome-wide studies, and also monogenic disorders. Finally, the legal and ethical complexities in dealing with these issues are discussed. Stroke Genetics is a valuable resource for neurologists, stroke physicians, hypertension specialists, internists, clinical pharmacologists and those in training, as well as researchers in the field of disease genetics. Each chapter now contains teaching/training MCQs to help with retention of information learnt from each chapter and this will be of considerable use to those training or about to the examined in the field of inherited stroke. Additional questions via app: Download the Springer Nature Flashcards app for free and use exclusive additional material to test your knowledge. Neurology . 66816 Internal medicine. Medical genetics. 64976 Neurology. 66816 Internal Medicine. Medical Genetics. 64976 Sharma, Pankaj. editor. edt http://id.loc.gov/vocabulary/relators/edt 74876 Meschia, James F. editor. edt http://id.loc.gov/vocabulary/relators/edt 74877 SpringerLink (Online service) Springer Nature eBook Printed edition: 9783031417764 Printed edition: 9783031417788 Printed edition: 9783031417795 https://doi.org/10.1007/978-3-031-41777-1 ZDB-2-SME ZDB-2-SXM 59014 59014