04067nam a22004815i 4500001001800000003000900018005001700027007001500044008004100059020001800100024003500118050001600153072001600169072002300185072001500208245018800223250001800411264007500429300006500504336002600569337002600595338003600621347002400657490004000681505111000721520120801831650001603039650001803055650002403073650002303097650001603120650001803136650002503154700007603179700007603255710003403331773002603365776003603391776003603427776003603463830004003499856004603539978-3-031-54960-1DE-He21320251030112055.0cr nn 008mamaa240523s2024    sz |    s    |||| 0|eng d  a97830315496017 a10.1007/978-3-031-54960-12doi 4aRC666-701.2 7aMJD2bicssc 7aMED0100002bisacsh 7aMJD2thema10aCardiovascular Outcomes Researchh[electronic resource] :bA Clinician’s Guide to Cardiovascular Epidemiology and Clinical Outcomes Trials /cedited by Kevin C. Maki, Don P. Wilson.  a1st ed. 2024. 1aCham :bSpringer International Publishing :bImprint: Springer,c2024.  aXVI, 438 p. 34 illus., 30 illus. in color.bonline resource.  atextbtxt2rdacontent  acomputerbc2rdamedia  aonline resourcebcr2rdacarrier  atext filebPDF2rda1 aContemporary Cardiology,x2196-89770 aChapter 1. History of Cardiovascular Epidemiology -- Chapter 2. Types of Cardiovascular Outcomes Studies -- Chapter 3. Basic Statistical Considerations for Cardiovascular Outcomes Studies -- Chapter 4. Evolving Concepts in Cardiovascular Outcomes Studies -- Chapter 5. Current Guidelines for Atherosclerotic Cardiovascular Disease Risk Reduction -- Chapter 6. Surrogate Markers of Cardiovascular Disease -- Chapter 7. Challenges in Developing Evidence-based Recommendations for Non-pharmacological Interventions for Atherosclerotic Cardiovascular Disease Risk Reduction -- Chapter 8. Overview of the Pharmaceutical Development Process for Agents to Influence Cardiovascular Health -- Chapter 9. Lipids and Cardiovascular Outcomes -- Chapter 10. Inflammation and Cardiovascular Outcomes -- Chapter 11. Hemostasis and Cardiovascular Outcomes -- Chapter 12. Cardiac Rhythms and Cardiovascular Outcomes -- Chapter 13. Blood Pressure and CardiovascularOutcomes -- Chapter 14. Diabetes, Obesity, Metabolic Syndrome and Cardiovascular Outcomes -- Chapter 15. Chronic Kidney Disease and Cardiovascular Outcomes. .  aThis book provides clinicians with the information needed to effectively interpret the literature from observational and interventional cardiovascular outcomes studies. The book begins by providing a historical context of cardiovascular epidemiology, followed by chapters addressing key concepts in the study of cardiovascular disease such as the types of cardiovascular outcomes studies, basic and evolving design and statistical considerations, current guidelines for reducing atherosclerotic cardiovascular disease risk, surrogate markers of cardiovascular disease, challenges in developing evidence-based recommendations for non-pharmacological interventions, an overview of the pharmaceutical development process, and a detailed discussion of the clinical evidence supporting several factors and their relationships with atherosclerotic cardiovascular disease (lipids, inflammation, hemostasis, heart rhythm, blood pressure, diabetes, obesity, and chronic kidney disease). Cardiovascular Outcomes Research is a must-have resource for physicians and other clinicians, residents, fellows, and medical students in cardiology, endocrinology, primary care, and health promotion and disease prevention. . 0aCardiology. 0aEpidemiology. 0aMedicinexResearch. 0aBiologyxResearch.14aCardiology.24aEpidemiology.24aBiomedical Research.1 aMaki, Kevin C.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt1 aWilson, Don P.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt2 aSpringerLink (Online service)0 tSpringer Nature eBook08iPrinted edition:z978303154959508iPrinted edition:z978303154961808iPrinted edition:z9783031549625 0aContemporary Cardiology,x2196-897740uhttps://doi.org/10.1007/978-3-031-54960-1