04585nam a22005055i 4500001001800000003000900018005001700027007001500044008004100059020003700100024003500137050001400172072001600186072002300202072001500225245015100240250001800391264007300409300006400482336002600546337002600572338003600598347002400634490003700658505073900695520197201434650004103406650003603447650003503483650002303518650003403541650003603575700008303611700008203694710003403776773002603810776003603836776003603872776003603908830004403944856004603988912001404034912001404048999001704062978-3-031-52696-1DE-He21320251030112100.0cr nn 008mamaa240527s2024    sz |    s    |||| 0|eng d  a97830315269619978-3-031-52696-17 a10.1007/978-3-031-52696-12doi 4aRC705-779 7aMJL2bicssc 7aMED0790002bisacsh 7aMJL2thema10aObesity and Lung Diseaseh[electronic resource] :bA Guide to Pathophysiology, Evaluation, and Management /cedited by Anne E. Dixon, Erick Forno.  a2nd ed. 2024. 1aCham :bSpringer International Publishing :bImprint: Humana,c2024.  aIX, 411 p. 41 illus., 30 illus. in color.bonline resource.  atextbtxt2rdacontent  acomputerbc2rdamedia  aonline resourcebcr2rdacarrier  atext filebPDF2rda1 aRespiratory Medicine,x2197-73800 aSECTION I: Pathophysiology of Obesity and Lung Disease -- Airway Physiology and Lung Function -- Immune Function and Host Defense -- The Microbiome -- Metabolic Dysregulation -- Genetics and Genomics -- Diet and Nutrition -- SECTION II: Obesity and Respiratory Diseases -- Obstructive Sleep Apnea -- Obesity Hypoventilation Syndrome -- Asthma: Epidemiology and Clinical Presentation -- Asthma: Endotypes and Mechanisms -- Asthma: Management -- Chronic Obstructive Pulmonary Disease -- Pulmonary Hypertension -- Thromboembolic Disease -- Lung Transplant -- Respiratory Infections (Including COVID19) -- Lung Health in Pediatrics -- SECTION III: Obesity and Critical Care -- ALI and ARDS -- Mechanical Ventilation -- COVID19 in the ICU.  aThis new edition provides a fully updated guide to obesity’s relation to lung disease. Over forty percent of the U.S. population is obese, and obesity is increasing in much of the world. Obesity has a major impact on health conditions such as diabetes and cardiovascular disease. The effects of obesity on lung disease have drawn increasing attention in recent years. Furthermore, the COVID pandemic has dramatically illustrated how obesity affects respiratory disease, constitutes a major risk factor for COVID-19, and presents challenges to pulmonary care in the ICU. Obesity changes physiology, immune and metabolic function, and is associated with changes in diet and the microbiome, all of which combine to have a major impact on the pathogenesis of respiratory diseases. Obesity is thus a risk factor for many respiratory diseases such as asthma, pulmonary hypertension, thromboembolic disease, obstructive sleep apnea and ARDS. Obesity also complicates the management of many other respiratory diseases and conditions such as COPD, thromboembolic disease, and the care of the critically ill patient. The objectives of this book are three-fold: To review how physiological, immune and metabolic factors might contribute to lung disease. To discuss the impact of obesity on common lung diseases To outline important considerations in the management of critically ill obese patients. There have been major advances in our understanding of the relationship between obesity and lung disease since the first edition in 2013, in addition to the major lessons learned about the importance of obesity during the COVID-19 pandemic. This has led to the addition of eight new chapters on topics such as, the microbiome, lung transplant, and COVID-19 in the ICU. This is an ideal guide for all clinicians taking care of patients with pulmonary and critical care diseases, as well as basic and translational scientists interested in how obesity affects respiratory health. 0aRespiratory organsxDiseases.977494 0aPrimary care (Medicine).964645 0aCritical care medicine.96304214aPneumology.97749524aPrimary Care Medicine.96464524aIntensive Care Medicine.9731981 aDixon, Anne E.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt9774961 aForno, Erick.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt9774972 aSpringerLink (Online service)0 tSpringer Nature eBook08iPrinted edition:z978303152695408iPrinted edition:z978303152697808iPrinted edition:z9783031526985 0aRespiratory Medicine,x2197-738097749840uhttps://doi.org/10.1007/978-3-031-52696-1  aZDB-2-SME  aZDB-2-SXM  c60151d60151