05075nam a22005895i 4500 978-3-031-42022-1 DE-He213 20251030112255.0 cr nn 008mamaa 240603s2024 sz | s |||| 0|eng d 9783031420221 978-3-031-42022-1 10.1007/978-3-031-42022-1 doi TP248.13-.65 TCB bicssc TEC009010 bisacsh TCB thema Di Paola, Luisa. author. aut http://id.loc.gov/vocabulary/relators/aut 78146 Fundamentals of Molecular Bioengineering [electronic resource] / by Luisa Di Paola. 1st ed. 2024. Cham : Springer International Publishing : Imprint: Springer, 2024. X, 271 p. 75 illus., 63 illus. in color. online resource. text txt rdacontent computer c rdamedia online resource cr rdacarrier text file PDF rda Part 1: Biomolecular Thermodynamics -- Chapter 1: Classical and Chemical Thermodynamics -- Chapter 2: Statistical hermodynamics -- chapter 3: Proteins -- Chapter 4: Intermolecular forces and potentials -- Chapter 5: Volumetric properties of fluids: equations of state -- Chapter 6: Biopolymers ionization and salting-out -- Chapter 7: Protein-ligand interactions and binding -- Part 2: Computational Biology -- Chapter 8: Molecular dynamics simulations for computational biology -- Chapter 9: Protein structure prediction and analysis -- Chapter 10: Systems biology and structure- based protein networks -- Chapter 11: Computational protein binding. This textbook covers the scientific basics of molecular bioengineering, a new field where technology meets biology and chemistry, and the fundamental knowledge required for students to understand molecular mechanisms beyond biological phenomena. The textbook focuses on the role of proteins in biomolecular machinery, and it is divided into 2 parts: Part I covers the molecular thermodynamics of biological systems, and Part II discusses the computational aspects behind protein structure prediction and molecular dynamics. In the first part of the textbook, students will find comprehensive explanations of thermodynamics and statistical mechanics, which are the basis to understand how molecular properties translate into macroscopic. Part I also offers an introduction to proteins and concepts like intermolecular forces, volumetric properties of fluids, ionization equilibria and salting-out, and protein binding and protein-protein interactions. In the second part of the textbook, students will learn about protein structure prediction and analysis, systems biology and structure-based protein networks, and computational tools and approaches for molecular dynamics simulations and protein binding and protein-protein interactions. This textbook adds to the scholarly debate with a unique contribution, addressing important new areas of biophysical chemistry and molecular biophysics not covered in currently available textbooks. Given its breadth, the textbook is suitable for courses in molecular biophysics, biochemistry, physical chemistry and bioengineering, and will also appeal to researchers and professionals in these fields. Part I of this book is a translation from its Italian original manuscript done with the help of artificial intelligence. A subsequent human revision of the content was done by the author. Springer Nature works continuously to further the development of tools for the production of books and on the related technologies to support the authors. This book is a translation of an original German edition. The translation was done with the help of artificial intelligence (machine translation by the service DeepL.com). A subsequent human revision was done primarily in terms of content, so that the book will read stylistically differently from a conventional translation. Biotechnology. 65162 Thermodynamics. 66400 Bioinformatics. 64050 Proteins . 70651 Chemistry Data processing. 69913 Biomedical engineering. Chemical Bioengineering. 67761 Thermodynamics. 66400 Computational and Systems Biology. 65974 Protein Biochemistry. 71768 Computational Chemistry. 69915 Biomedical Engineering and Bioengineering. SpringerLink (Online service) Springer Nature eBook Printed edition: 9783031420214 Printed edition: 9783031420238 Printed edition: 9783031420245 https://doi.org/10.1007/978-3-031-42022-1 ZDB-2-CMS ZDB-2-SXC 60467 60467