02586nam a22004335i 4500001001800000003000900018005001700027007001500044008004100059020001800100024003500118050001200153072001700165072002300182072001600205245015700221250001800378264006900396300005300465336002600518337002600544338003600570347002400606520110300630650002301733650001201756650001801768650001401786650002001800650002701820650001401847700007701861710003401938773002601972776003601998776003602034776003602070856004602106978-3-031-52860-6DE-He21320251030112255.0cr nn 008mamaa240603s2024    sz |    s    |||| 0|eng d  a97830315286067 a10.1007/978-3-031-52860-62doi 4aRC270.8 7aMJCL2bicssc 7aMED0620002bisacsh 7aMJCL2thema10aOvercoming Breast Cancer Therapy Resistanceh[electronic resource] :bFrom Mechanisms to Precision and AI-Powered Approaches /cedited by Zodwa Dlamini.  a1st ed. 2024. 1aCham :bSpringer Nature Switzerland :bImprint: Springer,c2024.  aIX, 394 p. 74 illus. in color.bonline resource.  atextbtxt2rdacontent  acomputerbc2rdamedia  aonline resourcebcr2rdacarrier  atext filebPDF2rda  aThis book addresses the pressing problem of drug resistance in the treatment of breast cancer. It provides a comprehensive understanding of the complex mechanisms underlying drug resistance and presents the latest advances in therapeutic approaches to overcome this enormous challenge. The book begins with an introduction to the biology of breast cancer, treatment modalities and the mechanisms of drug resistance. This includes the principles of drug resistance in targeted, immune-, endocrine and chemotherapy. In the following sections, the authors present innovative strategies to overcome drug resistance and new research directions, among others the role of the microbiome in drug resistance, molecular profiling of patients for personalized medical care, and new drug delivery systems. Finally, the book concludes with a discussion of the differences in the prevalence and treatment success of breast cancer between high- and low-income countries. This book is an informative resource for students, researchers, and clinicians in the field of breast cancer research and oncology in general. 0aCancerxTreatment. 0aCancer. 0aNanomedicine. 0aOncology.14aCancer Therapy.24aCancer Nanotechnology.24aOncology.1 aDlamini, Zodwa.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt2 aSpringerLink (Online service)0 tSpringer Nature eBook08iPrinted edition:z978303152859008iPrinted edition:z978303152861308iPrinted edition:z978303152862040uhttps://doi.org/10.1007/978-3-031-52860-6