03733nam a22005895i 4500 978-981-97-1651-7 DE-He213 20251030112318.0 cr nn 008mamaa 240618s2024 si | s |||| 0|eng d 9789819716517 978-981-97-1651-7 10.1007/978-981-97-1651-7 doi QD415-436 PSB bicssc SCI007000 bisacsh PSB thema Agarwal, Ritu. author. aut http://id.loc.gov/vocabulary/relators/aut 78878 Modeling Calcium Signaling [electronic resource] : A Fractional Perspective / by Ritu Agarwal, Sunil Dutt Purohit, Kritika. 1st ed. 2024. Singapore : Springer Nature Singapore : Imprint: Springer, 2024. XII, 76 p. 25 illus., 23 illus. in color. online resource. text txt rdacontent computer c rdamedia online resource cr rdacarrier text file PDF rda SpringerBriefs in Biochemistry and Molecular Biology, 2211-9361 Chapter 1 Introduction to Fractional Calculus and Modeling -- Chapter 2 Cytosolic Calcium Distribution and Thrombin Receptor Activation -- Chapter 3 Effects of Buffers over the Cytosolic Calcium Concentration -- Chapter 4 Anomalous Subdiffusive Behaviour of Cytosolic Calcium. This book focuses on the fundamental processes involved in calcium signaling through fractional mathematical modeling. The intended reader of the book is mathematically proficient students of cell biology, applied mathematics and mathematical biology who are interested in learning about modeling in cell biology. The book inspires the graduate students and researchers to collaborate with experimentalists while studying the direction needed to explore the modeling literature. Organized into four chapters, the book introduces fractional calculus and is devoted to understanding the receptor activation by the ligand, that is Thrombin via fractional model incorporating the Caputo-Fabrizio fractional operator. It studies the calcium profile in red blood cells with the help of the advection-diffusion equation. The book further studies the process of buffering, aiding the lowering of the calcium concentration in the cytosol, which rises due to calcium influx from extracellular space and intracellular storage. It explains the concept of anomalous diffusion—a mathematical model is proposed to characterize the anomalous subdiffusion of cytosolic calcium. Biochemistry. 65465 Molecular biology. Cytology. 67436 Mathematical optimization. 65522 Calculus of variations. 67268 Biochemistry. 65465 Molecular Biology. Cell Biology. 67440 Calculus of Variations and Optimization. 67270 Purohit, Sunil Dutt. author. aut http://id.loc.gov/vocabulary/relators/aut 78879 Kritika. author. aut http://id.loc.gov/vocabulary/relators/aut 78880 SpringerLink (Online service) Springer Nature eBook Printed edition: 9789819716500 Printed edition: 9789819716524 SpringerBriefs in Biochemistry and Molecular Biology, 2211-9361 78881 https://doi.org/10.1007/978-981-97-1651-7 ZDB-2-CMS ZDB-2-SXC 60814 60814