04091nam a22006015i 4500 978-981-97-0511-5 DE-He213 20251030112616.0 cr nn 008mamaa 240705s2024 si | s |||| 0|eng d 9789819705115 978-981-97-0511-5 10.1007/978-981-97-0511-5 doi QR180-189.5 MJCM bicssc MED044000 bisacsh MJCM thema Non B cell-Derived Immunoglobulins [electronic resource] : The Structure, Characteristics and the Implication on Clinical Medicine / edited by Xiaoyan Qiu, Jing Huang, Xiaojun Xu. 1st ed. 2024. Singapore : Springer Nature Singapore : Imprint: Springer, 2024. XIV, 188 p. 31 illus. in color. online resource. text txt rdacontent computer c rdamedia online resource cr rdacarrier text file PDF rda Advances in Experimental Medicine and Biology, 2214-8019 ; 1445 Chapter 1 The history of appreciation of immunoglobulin and the discovery of non-B cell derived immunoglobulins -- Chapter 2 Expression profile of non B-Ig in different lineage cells -- Chapter 3 Unique V(D)J recombination characteristics and repertoire of non B-Ig -- Chapter 4 Unique regulation mechanismof non B-Ig gene -- Chapter 5 Unique structure and function of non B-Ig -- Chapter 6 Comparison of non B-Ig and B-Ig -- Chapter 7 Functionsand clinical relevanceof non-B cell derived immunoglobulin in liver -- Chapter 8 Significance of non-Bcell derived immunoglobulins in renal disease -- Chapter 9 Functions and clinical significance of myocardial cell-derived Immunoglobulins -- Chapter 10 Biological functions and clinical significance of intestinal non B-Immunoglobulins -- Chapter 11 Function of IgG and IgA in normal human skin -- Chapter 12 Significance of cancer-derived IgG in lung cancer -- Chapter 13 Significance of cancer-derived IgG in breast cancer -- Chapter 14 Significance of cancer-derived IgG in pancreatic cancer -- Chapter 15 Biological functions and clinical significance of non B-Ig in hemopoietic system. This book has expanded classic concept of immunology. Immunoglobulins have been widely discovered to be produced by many non-B cells. The non B cell-derived Igs display multifunction, which not only includes antibody activities and cellular biological functions under physiological conditions, but also directly participate in the pathological process of malignant tumour and immune-related diseases. This book provides new perspectives and a solid foundation for medical students, basic and clinical scientists to re-understand and broaden the physiological and pathological significance of Ig. Immunology. 69214 Medicine Research. 62598 Biology Research. 65629 Life sciences. 65072 Immunology. 69214 Biomedical Research. 65633 Life Sciences. 65072 Biomedical Research. 65633 Qiu, Xiaoyan. editor. edt http://id.loc.gov/vocabulary/relators/edt 80112 Huang, Jing. editor. edt http://id.loc.gov/vocabulary/relators/edt 80113 Xu, Xiaojun. editor. edt http://id.loc.gov/vocabulary/relators/edt 80114 SpringerLink (Online service) Springer Nature eBook Printed edition: 9789819705108 Printed edition: 9789819705122 Printed edition: 9789819705139 Advances in Experimental Medicine and Biology, 2214-8019 ; 1445 67831 https://doi.org/10.1007/978-981-97-0511-5 ZDB-2-SBL ZDB-2-SXB 61382 61382