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  <titleInfo>
    <title>Non B cell-Derived Immunoglobulins</title>
    <subTitle>The Structure, Characteristics and the Implication on Clinical Medicine</subTitle>
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    <namePart>Qiu, Xiaoyan.</namePart>
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    <namePart>Huang, Jing.</namePart>
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    <namePart>Xu, Xiaojun.</namePart>
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    <dateIssued encoding="marc">2024</dateIssued>
    <edition>1st ed. 2024.</edition>
    <issuance>monographic</issuance>
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    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
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    <extent>XIV, 188 p. 31 illus. in color. online resource.</extent>
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  <abstract>This book has expanded classic concept of immunology. Immunoglobulins have been widely discovered to be produced by many non-B cells. The non B cell-derived Igs display multifunction, which not only includes antibody activities and cellular biological functions under physiological conditions, but also directly participate in the pathological process of malignant tumour and immune-related diseases. This book provides new perspectives and a solid foundation for medical students, basic and clinical scientists to re-understand and broaden the physiological and pathological significance of Ig.</abstract>
  <tableOfContents>Chapter 1 The history of appreciation of immunoglobulin and the discovery of non-B cell derived immunoglobulins -- Chapter 2 Expression profile of non B-Ig in different lineage cells -- Chapter 3 Unique V(D)J recombination characteristics and repertoire of non B-Ig -- Chapter 4 Unique regulation mechanismof non B-Ig gene -- Chapter 5 Unique structure and function of non B-Ig -- Chapter 6 Comparison of non B-Ig and B-Ig -- Chapter 7 Functionsand clinical relevanceof non-B cell derived immunoglobulin in liver -- Chapter 8 Significance of non-Bcell derived immunoglobulins in renal disease -- Chapter 9 Functions and clinical significance of myocardial cell-derived Immunoglobulins -- Chapter 10 Biological functions and clinical significance of intestinal non B-Immunoglobulins -- Chapter 11 Function of IgG and IgA in normal human skin -- Chapter 12 Significance of cancer-derived IgG in lung cancer -- Chapter 13 Significance of cancer-derived IgG in breast cancer -- Chapter 14 Significance of cancer-derived IgG in pancreatic cancer -- Chapter 15 Biological functions and clinical significance of non B-Ig in hemopoietic system.</tableOfContents>
  <note type="statement of responsibility">edited by Xiaoyan Qiu, Jing Huang, Xiaojun Xu.</note>
  <subject authority="lcsh">
    <topic>Immunology</topic>
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  <subject authority="lcsh">
    <topic>Medicine</topic>
    <topic>Research</topic>
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  <subject authority="lcsh">
    <topic>Biology</topic>
    <topic>Research</topic>
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  <subject authority="lcsh">
    <topic>Life sciences</topic>
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  <subject>
    <topic>Immunology</topic>
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  <subject>
    <topic>Biomedical Research</topic>
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  <subject>
    <topic>Life Sciences</topic>
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  <subject>
    <topic>Biomedical Research</topic>
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    <titleInfo>
      <title>Advances in Experimental Medicine and Biology, 1445</title>
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  <identifier type="isbn">9789819705115</identifier>
  <identifier type="uri">https://doi.org/10.1007/978-981-97-0511-5</identifier>
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