04244nam a22005535i 4500 978-3-031-62983-9 DE-He213 20251030112630.0 cr nn 008mamaa 240715s2024 sz | s |||| 0|eng d 9783031629839 978-3-031-62983-9 10.1007/978-3-031-62983-9 doi RC321-580 PSAN bicssc SCI089000 bisacsh PSAN thema Engrams [electronic resource] : A Window into the Memory Trace / edited by Johannes Gräff, Steve Ramirez. 1st ed. 2024. Cham : Springer International Publishing : Imprint: Springer, 2024. XV, 304 p. 34 illus., 32 illus. in color. online resource. text txt rdacontent computer c rdamedia online resource cr rdacarrier text file PDF rda Advances in Neurobiology, 2190-5223 ; 38 Section I: Introduction -- Engrams to remember – A conversation between Johannes and Steve -- Section II: Engram cells and their mnemonic role across different brain structures -- Engrams: From behavior to brain-wide networks -- Memory storage in distributed engram cell ensembles -- Hippocampal engrams and contextual memory -- The role of prefrontal ensembles in memory across time – Time-dependent transformations of prefrontal memory ensembles -- Section III: Insights into intra-engram functioning -- All IEGs are not created equal – Molecular sorting within the memory engram -- Unveiling transcriptional and epigenetic mechanisms within engram cells: Insights into memory formation and stability -- The synaptic engram -- Section IV: Beyond associative learning: Engrams for other memory processes -- Engrams of fear memory attenuation -- Adult neurogenesis, context encoding, and pattern separation: A pathway for treating overgeneralization -- What can hippocampal engrams tell us about encoding spatial navigation? -- Understanding others’ distress through past experiences: The role of memory engram cells in observational fear -- Section V: Beyond the neurobiology of engrams -- A computational framework for memory engrams -- Engram studies: A call for historical, philosophical and sociological approaches -- If engrams are the answer, what is the question?. This is the first book to extensively explore the current state-of-the-art and promise of engram cells, the closest physical approximation of the memory trace to date. Converging evidence suggests that memories are stored, at least in part, as specific populations of engram cells. In this book, the leading experts in engram biology share their continuously refined insights on how engram cells contribute to information encoding and storage, across diverse brain regions and behavioral modalities. “Engrams: A Window into the Memory Trace" is broad in scope and spans molecular, cellular, circuit, computational as well as societal-philosophical aspects of memory engrams. Particular emphasis is placed on their emerging translational value for memory dysfunctions in age and stress-related disorders. . Neurosciences. 68384 Neuropsychology. 72983 Psychobiology. 73728 Neuroscience. 68386 Neuropsychology. 72983 Biological Psychology. 80607 Gräff, Johannes. editor. edt http://id.loc.gov/vocabulary/relators/edt 80608 Ramirez, Steve. editor. edt http://id.loc.gov/vocabulary/relators/edt 80609 SpringerLink (Online service) Springer Nature eBook Printed edition: 9783031629822 Printed edition: 9783031629846 Printed edition: 9783031629853 Advances in Neurobiology, 2190-5223 ; 38 72663 https://doi.org/10.1007/978-3-031-62983-9 ZDB-2-SBL ZDB-2-SXB 61616 61616