04154nam a22006135i 4500 978-981-10-1941-8 DE-He213 20251030112840.0 cr nn 008mamaa 240806s2024 si | s |||| 0|eng d 9789811019418 978-981-10-1941-8 10.1007/978-981-10-1941-8 doi QD95-96 PNFS bicssc SCI013050 bisacsh PNFS thema Xiao, Jianxi. author. (orcid)0000-0002-9863-572X https://orcid.org/0000-0002-9863-572X aut http://id.loc.gov/vocabulary/relators/aut 81980 Collagen Mimetic Peptides and Their Biophysical Characterization [electronic resource] / by Jianxi Xiao. 1st ed. 2024. Singapore : Springer Nature Singapore : Imprint: Springer, 2024. XV, 226 p. 108 illus., 96 illus. in color. online resource. text txt rdacontent computer c rdamedia online resource cr rdacarrier text file PDF rda Springer Series in Biomaterials Science and Engineering, 2195-0652 ; 20 Introduction to collagen -- Structure of collagen triple helix -- Bioinformatics-aided Design of collagen mimic peptides -- Synthesis of collagen peptides -- CD characterization of triple helix stability -- Structural insights from X-ray crystallography -- Conformational and dynamic characterization by NMR spectroscopy -- Fluorescence detection of collagen biomarkers -- Synthesis and characterization of heterotrimeric models of collagen -- Self-assembly of collagen mimic peptides -- Concluding remarks. This book embarks on an enlightening journey through the molecular landscape of collagen mimic peptides, shedding light on their significance and potential. In the intricate realm of biomolecules, collagen's preeminence as the most abundant protein in the human body, forming the foundational scaffolding of tissues and organs, renders it a subject of profound scientific interest. It explores diverse facets related to collagen mimic peptides, spanning aspects such as bioinformatic analysis, synthetic strategies, pathological collagen targeting, and the construction of homotrimeric, heterotrimeric and self-assembled peptide models. Furthermore, it provides an exhaustive investigation into biophysical techniques, encompassing Circular Dichroism (CD), X-ray crystallography, Nuclear Magnetic Resonance (NMR), Fluorescence, and Raman spectroscopy, thereby empowering researchers to unravel the structural intricacies of these peptides. The book unravels the profound implications of collagen mimic peptides across a spectrum of scientific domains, including protein science, biomaterials, bioanalysis, and beyond. Its accessibility and insights cater not only to seasoned researchers but also to undergraduate and graduate students eager to delve into the complexities of this fundamental protein. Spectrum analysis. 69373 Biophysics. 66239 Biomaterials. Regenerative medicine. 67458 Bioorganic chemistry. Materials Analysis. Spectroscopy. 69375 Biophysics. 66239 Biomaterials. Regenerative Medicine and Tissue Engineering. 67459 Bioorganic Chemistry. Characterization and Analytical Technique. 66416 SpringerLink (Online service) Springer Nature eBook Printed edition: 9789811019401 Printed edition: 9789811019425 Printed edition: 9789819776696 Springer Series in Biomaterials Science and Engineering, 2195-0652 ; 20 81981 https://doi.org/10.1007/978-981-10-1941-8 ZDB-2-CMS ZDB-2-SXC 62276 62276