04822nam a22005295i 4500001001800000003000900018005001700027007001500044008004100059020003700100024003500137050000700172072001500179072002300194072001400217100008600231245016500317250001800482264008200500300006600582336002600648337002600674338003600700347002400736505130400760520164502064650002903709650002503738650003303763650002403796650002303820650002803843650002803871650002503899650005103924650002203975650002303997650004904020710003404069773002604103776003604129776003604165856004604201912001404247912001404261999001704275978-3-662-68904-2DE-He21320251030112859.0cr nn 008mamaa240819s2024 gw | s |||| 0|eng d a97836626890429978-3-662-68904-27 a10.1007/978-3-662-68904-22doi 4aR1 7aMB2bicssc 7aMED0000002bisacsh 7aMB2thema1 aStraub, Rainer H.eauthor.4aut4http://id.loc.gov/vocabulary/relators/aut98253210aUnderstanding Aging, Fatigue, and Inflammationh[electronic resource] :bWhen the Immune System and Brain Compete for Energy in the Body /cby Rainer H. Straub. a1st ed. 2024. 1aBerlin, Heidelberg :bSpringer Berlin Heidelberg :bImprint: Springer,c2024. aXVII, 210 p. 39 illus., 38 illus. in color.bonline resource. atextbtxt2rdacontent acomputerbc2rdamedia aonline resourcebcr2rdacarrier atext filebPDF2rda0 aI Energy, evolution and medicine 1 Energy and the body -- 2 Evolutionary medicine -- 3 The brain and the immune system - two competing realms -- II Energy expenditure in the spotlight 4 Inflammation and energy -- 5 Pain and energy -- 6 Psychological stress and energy -- 7 Other energy-draining situations -- 8 What does increased energy expenditure mean for the body -- III From energy and evolution to symptoms 9 Daytime tiredness and depression -- 10 Sleep disorders and symptoms related to the time of day -- 11 Loss of appetite - malnutrition and malnutrition -- 12 Muscle wasting -- 13 Bone loss - osteoporosis -- 14 Weight changes (increase and decrease) -- 15 Storage hormones (increase and decrease). 11 Loss of appetite, malnutrition and malnutrition -- 12 Muscle atrophy -- 13 Bone atrophy - osteoporosis -- 14 Weight changes (gain and loss) -- 15 The storage hormone insulin doesn't do it - insulin resistance -- 16 Dwindling libido, lower fertility -- 17 The sympathetic nervous system fires the insulin hormone. 17 Sympathetic nervous system fires and causes high blood pressure -- 18 Increased blood clotting - thromboses/embolisms -- 19 Stress worsens inflammation and inflammation changes stress resilience -- 20 The big summary: unwanted energy expenditure -- Glossary -- Appendix. aIn this scientific non-fiction book, Rheumatologist and Professor of Experimental Medicine Rainer H. Straub holistically explains a central conflict in the body: why the battle for energy leads to aging and fatigue, stress, sleep disorders, weight problems, libido issues, and hypertension. He explores how this particularly affects people with chronic inflammatory diseases. With fascinating insights, the author takes us on a journey into evolutionary biology, the present state of energy regulation, and the forward-looking field of psychoneuroimmunology. Learn to understand the connections between inflammatory processes and energy regulation in the body, drawing implications for disease pathophysiology and for therapeutic possibilities. From the contents Energy and the body - Evolutionary medicine - Brain and immune system - two competing organs - Inflammation and energy - Pain and energy - Psychological stress and energy - What does increased energy expenditure means for the body? – Fatigue - sleep disorders - loss of appetite – malnutrition - muscle and bone loss - insulin resistance - libido and fertility – hypertension - thrombosis and embolisms - stress worsens inflammation and inflammation changes stress tolerance. The Author Professor Dr. med. Rainer H. Straub is Professor of Experimental Medicine and Rheumatologist. He heads the Laboratory for Experimental Rheumatology and Neuroendocrine Immunology, Department of Internal Medicine at the University Hospital Regensburg. The translation was done with the help of artificial intelligence. A subsequent human revision was done primarily in terms of content. 0aMedical sciences.965984 0aRheumatology.972809 0aAlternative medicine.970733 0aNeurology .966816 0aImmunology.969214 0aFamily medicine.96333914aHealth Sciences.96598724aRheumatology.97280924aComplementary and Alternative Medicine.97073624aNeurology.96681624aImmunology.96921424aGeneral Practice and Family Medicine.9732912 aSpringerLink (Online service)0 tSpringer Nature eBook08iPrinted edition:z978366268903508iPrinted edition:z978366268905940uhttps://doi.org/10.1007/978-3-662-68904-2 aZDB-2-SBL aZDB-2-SXB c62559d62559