04060nam a22005415i 4500 978-981-97-5016-0 DE-He213 20251030112919.0 cr nn 008mamaa 240829s2024 si | s |||| 0|eng d 9789819750160 978-981-97-5016-0 10.1007/978-981-97-5016-0 doi RS199.5 TCB bicssc SCI010000 bisacsh TCB thema Drug Repurposing [electronic resource] : Innovative Approaches to Drug Discovery and Development / edited by Naveen Chella, Om Prakash Ranjan, Amit Alexander. 1st ed. 2024. Singapore : Springer Nature Singapore : Imprint: Springer, 2024. XIII, 248 p. 34 illus., 33 illus. in color. online resource. text txt rdacontent computer c rdamedia online resource cr rdacarrier text file PDF rda Chapter 1. Drug repurposing: History, Significance, Benefits, Approaches and Challenges -- Chapter 2. Methodologies Adopted in Drug Repurposing -- Chapter 3. In silico methods used in drug repurposing -- Chapter 4. Role of artificial and machine learning in drug repurposing -- Chapter 5. Drug repurposing in cancer therapy -- Chapter 6. Drug repurposing in inflammatory disorders -- Chapter 7. Drug repurposing in CNS disorders -- Chapter 8. Reshaping the Therapeutic Landscape: Drug Repurposing for Emerging Infectious Diseases and Rare Diseases -- Chapter 9. Clinical trials on repurposed drugs: an overview -- Chapter 10. Intellectual Property Rights and Regulatory Considerations Throughout Drug Repurposing -- Chapter 11. Redirection to the Drug Discovery: Antidiabetic Drugs Repurposing in Cancer. This book offers an insightful exploration of drug repurposing, an innovative approach to drug discovery and development that has the potential to revolutionize the field of medicine. It begins with an introduction to drug repurposing and its history, providing a comprehensive overview of the subject. The readers will embark on a journey through the diverse landscape of drug repurposing strategies. From in silico methods of predicting drug-disease associations to experimental approaches to the integrations of artificial intelligence (AI) and machine learning (ML) in drug repurposing for validating repurposed candidates. The book also delves into the application of drug repurposing in various disease areas, including cancer, inflammatory disorders, and CNS disorders. It explores the potential hurdles involved in the regulatory aspects of the process. The book further covers drug products under clinical trials and provides an overview of the future perspectives of drug repurposing. With its detailed and informative content, this book is a must-read for researchers, clinicians, and healthcare professionals interested in the exciting field of drug repurposing. Drug delivery systems. Pharmacovigilance. 74275 Diseases. 68840 Drug Delivery. 69429 Drug Safety and Pharmacovigilance. 74276 Diseases. 68840 Chella, Naveen. editor. edt http://id.loc.gov/vocabulary/relators/edt 83168 Ranjan, Om Prakash. editor. edt http://id.loc.gov/vocabulary/relators/edt 83169 Alexander, Amit. editor. edt http://id.loc.gov/vocabulary/relators/edt 83170 SpringerLink (Online service) Springer Nature eBook Printed edition: 9789819750153 Printed edition: 9789819750177 Printed edition: 9789819750184 https://doi.org/10.1007/978-981-97-5016-0 ZDB-2-SBL ZDB-2-SXB 62850 62850