03283nam a22005055i 4500001001800000003000900018005001700027007001500044008004100059020001800100024003500118050001400153072001700167072002300184072001600207100008000223245014800303250001800451264006900469300006500538336002600603337002600629338003600655347002400691505054100715520103101256650001902287650003002306650001602336650002202352650002202374650002402396650002302420650001802443650002802461650002302489650002602512650002502538710003402563773002602597776003602623776003602659776003602695856004602731978-3-031-69549-0DE-He21320251030113032.0cr nn 008mamaa240910s2024 sz | s |||| 0|eng d a97830316954907 a10.1007/978-3-031-69549-02doi 4aRC321-580 7aPSAN2bicssc 7aSCI0890002bisacsh 7aPSAN2thema1 aMayevsky, Avraham.eauthor.4aut4http://id.loc.gov/vocabulary/relators/aut14aThe Mongolian Gerbil Brainh[electronic resource] :bMitochondrial Function, Vasculature, and Pathophysiological States /cby Avraham Mayevsky. a1st ed. 2024. 1aCham :bSpringer Nature Switzerland :bImprint: Springer,c2024. aIX, 340 p. 227 illus., 34 illus. in color.bonline resource. atextbtxt2rdacontent acomputerbc2rdamedia aonline resourcebcr2rdacarrier atext filebPDF2rda0 aChapter 1 Historical Background of the Mongolian Gerbil in Research -- Chapter 2 Brain Energy Metabolism and mitochondrial function -- Chapter 3 Brain Real Time Monitoring systems used in Gerbils -- Chapter 4 Brain vasculature in the Mongolian Gerbil's -- Chapter 5 Brain Multisite recording under brain perturbations -- Chapter 6 Multiparametric Responses to Brain Oxygen Supply -- Chapter 7 Multiparametric Responses to Brain Activation -- Chapter 8 Neuroprotactants effect on the Gerbil Brain -- Chapter 9 Discussion and Conclusions. aThe Mongolian gerbil brain lies in the anatomy of the blood vessels supplying blood to the brain. In all mammals, there is a special mechanism that compensates for the decreased blood flow to the brain in the case of development of stroke. This mechanism is missing in the gerbil and therefore makes the Mongolian gerbil a unique model for stroke. Dr. Mayevsky adopted the gerbil as a model for stroke and his laboratory uniquely studied the mitochondria in the gerbil brain under various pathophysiological conditions. This book describes the history of the Mongolian gerbil in research, the brain energy metabolism and mitochondrial function and brain real-time monitoring systems used in gerbils, as well as the brain vasculature of the Mongolian gerbil. Further, the book includes chapters on brain multisite recording under brain perturbations, multiparametric responses to brain activation, and the effect of neuroprotectants on the gerbil brain. This is an ideal book for research teams researching stroke and epilepsy. 0aNeurosciences. 0aNervous systemxDiseases. 0aPhysiology. 0aMedical sciences. 0aDrug development. 0aMedicinexResearch. 0aBiologyxResearch.14aNeuroscience.24aNeurological Disorders.24aAnimal Physiology.24aPreclinical Research.24aBiomedical Research.2 aSpringerLink (Online service)0 tSpringer Nature eBook08iPrinted edition:z978303169548308iPrinted edition:z978303169550608iPrinted edition:z978303169551340uhttps://doi.org/10.1007/978-3-031-69549-0