The Mitochondrial Function, Vasculature, and Pathophysiological States Mayevsky, Avraham. creator author. aut http://id.loc.gov/vocabulary/relators/aut SpringerLink (Online service) text sz 2024 1st ed. 2024. monographic eng

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access IX, 340 p. 227 illus., 34 illus. in color. online resource. The Mongolian gerbil brain lies in the anatomy of the blood vessels supplying blood to the brain. In all mammals, there is a special mechanism that compensates for the decreased blood flow to the brain in the case of development of stroke. This mechanism is missing in the gerbil and therefore makes the Mongolian gerbil a unique model for stroke. Dr. Mayevsky adopted the gerbil as a model for stroke and his laboratory uniquely studied the mitochondria in the gerbil brain under various pathophysiological conditions. This book describes the history of the Mongolian gerbil in research, the brain energy metabolism and mitochondrial function and brain real-time monitoring systems used in gerbils, as well as the brain vasculature of the Mongolian gerbil. Further, the book includes chapters on brain multisite recording under brain perturbations, multiparametric responses to brain activation, and the effect of neuroprotectants on the gerbil brain. This is an ideal book for research teams researching stroke and epilepsy. Chapter 1 Historical Background of the Mongolian Gerbil in Research -- Chapter 2 Brain Energy Metabolism and mitochondrial function -- Chapter 3 Brain Real Time Monitoring systems used in Gerbils -- Chapter 4 Brain vasculature in the Mongolian Gerbil's -- Chapter 5 Brain Multisite recording under brain perturbations -- Chapter 6 Multiparametric Responses to Brain Oxygen Supply -- Chapter 7 Multiparametric Responses to Brain Activation -- Chapter 8 Neuroprotactants effect on the Gerbil Brain -- Chapter 9 Discussion and Conclusions. by Avraham Mayevsky. Neurosciences Nervous system Diseases Physiology Medical sciences Drug development Medicine Research Biology Research Neuroscience Neurological Disorders Animal Physiology Preclinical Research Biomedical Research RC321-580 9783031695490 https://doi.org/10.1007/978-3-031-69549-0 https://doi.org/10.1007/978-3-031-69549-0 240910 20251030113032.0 978-3-031-69549-0