03616nam a22005775i 4500 978-3-031-62232-8 DE-He213 20251030113047.0 cr nn 008mamaa 240917s2024 sz | s |||| 0|eng d 9783031622328 978-3-031-62232-8 10.1007/978-3-031-62232-8 doi QH573-671 PSF bicssc SCI017000 bisacsh PSF thema Molecular and Cell Biology of Pancreas Development, Function and Regeneration [electronic resource] / edited by Maria L. Golson. 1st ed. 2024. Cham : Springer International Publishing : Imprint: Springer, 2024. VII, 197 p. 18 illus., 17 illus. in color. online resource. text txt rdacontent computer c rdamedia online resource cr rdacarrier text file PDF rda Advances in Anatomy, Embryology and Cell Biology, 2192-7065 ; 239 Alpha Cell Contribution to Glucose Homeostasis -- Delta Cell Contribution to Glucose Homeostasis -- Islet Cell Plasticity Including Beta-Cell Dedifferentiation—Combined with Beta-Cell Heterogeneity -- Epigenetic Regulation of Pancreas Development and Function -- Beta-Cell Differentiation in vitro -- Endocrine Pancreas Regeneration -- Ductal Cell Development -- Relationship Between Beta-Cell Function and Beta-Cell Proliferation -- Maternal and Paternal Environmental Impacts on Beta-Cell Development -- Beyond Sugar: How Fat and Protein Contribute to the Regulation of Insulin Secretion -- Channels Involved in Regulating Insulin Secretion. This book reviews recent advances in pancreatic endocrine and exocrine tissue development, function and regeneration. It provides a comprehensive overview on different aspects of beta-cell biology, including heterogeneity of function and gene expression and function, epigenetics, RNA and protein expression contributions to beta-cell specification and cell-fate maintenance. Furthermore, it covers recent progress in differentiating functional islets in vivo, environmental impacts on beta-cell development and function, and communications between various islet endocrine cells and how they contribute to the regulation of blood glucose homeostasis. The book provides a comprehensive resource for understanding the various compartments of the pancreas and is aimed at pancreas, beta-cell biology, and diabetes researchers. Cytology. 67436 Digestion. 84453 Physiology. 72764 Gastrointestinal system. 76829 Gastrointestinal System. 76829 Internal medicine. Cell Biology. 67440 Digestive System Physiology. 84454 Gastrointestinal System. 76829 Internal Medicine. Golson, Maria L. editor. edt http://id.loc.gov/vocabulary/relators/edt 84455 SpringerLink (Online service) Springer Nature eBook Printed edition: 9783031622311 Printed edition: 9783031622335 Advances in Anatomy, Embryology and Cell Biology, 2192-7065 ; 239 80867 https://doi.org/10.1007/978-3-031-62232-8 ZDB-2-SBL ZDB-2-SXB 63447 63447