<?xml version="1.0" encoding="UTF-8"?>
<mods xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns="http://www.loc.gov/mods/v3" version="3.1" xsi:schemaLocation="http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-1.xsd">
  <titleInfo>
    <title>Molecular and Cell Biology of Pancreas Development, Function and Regeneration</title>
  </titleInfo>
  <name type="personal">
    <namePart>Golson, Maria L.</namePart>
    <role>
      <roleTerm type="text">editor.</roleTerm>
    </role>
    <role>
      <roleTerm authority="marcrelator" type="code">edt</roleTerm>
    </role>
    <role>
      <roleTerm authority="marcrelator" type="code">http://id.loc.gov/vocabulary/relators/edt</roleTerm>
    </role>
  </name>
  <name type="corporate">
    <namePart>SpringerLink (Online service)</namePart>
  </name>
  <typeOfResource>text</typeOfResource>
  <originInfo>
    <place>
      <placeTerm type="code" authority="marccountry">sz</placeTerm>
    </place>
    <dateIssued encoding="marc">2024</dateIssued>
    <edition>1st ed. 2024.</edition>
    <issuance>monographic</issuance>
  </originInfo>
  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
  </language>
  <physicalDescription>
    <form authority="marcform">electronic</form>
    <form authority="gmd">electronic resource</form>
    <reformattingQuality>access</reformattingQuality>
    <extent>VII, 197 p. 18 illus., 17 illus. in color. online resource.</extent>
  </physicalDescription>
  <abstract>This book reviews recent advances in pancreatic endocrine and exocrine tissue development, function and regeneration. It provides a comprehensive overview on different aspects of beta-cell biology, including heterogeneity of function and gene expression and function, epigenetics, RNA and protein expression contributions to beta-cell specification and cell-fate maintenance. Furthermore, it covers recent progress in differentiating functional islets in vivo, environmental impacts on beta-cell development and function, and communications between various islet endocrine cells and how they contribute to the regulation of blood glucose homeostasis. The book provides a comprehensive resource for understanding the various compartments of the pancreas and is aimed at pancreas, beta-cell biology, and diabetes researchers.</abstract>
  <tableOfContents>Alpha Cell Contribution to Glucose Homeostasis -- Delta Cell Contribution to Glucose Homeostasis -- Islet Cell Plasticity Including Beta-Cell Dedifferentiation—Combined with Beta-Cell Heterogeneity -- Epigenetic Regulation of Pancreas Development and Function -- Beta-Cell Differentiation in vitro -- Endocrine Pancreas Regeneration -- Ductal Cell Development -- Relationship Between Beta-Cell Function and Beta-Cell Proliferation -- Maternal and Paternal Environmental Impacts on Beta-Cell Development -- Beyond Sugar: How Fat and Protein Contribute to the Regulation of Insulin Secretion -- Channels Involved in Regulating Insulin Secretion.</tableOfContents>
  <note type="statement of responsibility">edited by Maria L. Golson.</note>
  <subject authority="lcsh">
    <topic>Cytology</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Digestion</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Physiology</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Gastrointestinal system</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Gastrointestinal System</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Internal medicine</topic>
  </subject>
  <subject>
    <topic>Cell Biology</topic>
  </subject>
  <subject>
    <topic>Digestive System Physiology</topic>
  </subject>
  <subject>
    <topic>Gastrointestinal System</topic>
  </subject>
  <subject>
    <topic>Internal Medicine</topic>
  </subject>
  <classification authority="lcc">QH573-671</classification>
  <relatedItem type="host">
    <titleInfo>
      <title>Springer Nature eBook</title>
    </titleInfo>
  </relatedItem>
  <relatedItem type="otherFormat" displayLabel="Printed edition:"/>
  <relatedItem type="otherFormat" displayLabel="Printed edition:"/>
  <relatedItem type="series">
    <titleInfo>
      <title>Advances in Anatomy, Embryology and Cell Biology, 239</title>
    </titleInfo>
  </relatedItem>
  <identifier type="isbn">9783031622328</identifier>
  <identifier type="uri">https://doi.org/10.1007/978-3-031-62232-8</identifier>
  <location>
    <url>https://doi.org/10.1007/978-3-031-62232-8</url>
  </location>
  <recordInfo>
    <recordCreationDate encoding="marc">240917</recordCreationDate>
    <recordChangeDate encoding="iso8601">20251030113047.0</recordChangeDate>
    <recordIdentifier source="DE-He213">978-3-031-62232-8</recordIdentifier>
  </recordInfo>
</mods>
