05014nam a22006375i 4500 978-3-031-59567-7 DE-He213 20251030113059.0 cr nn 008mamaa 240805s2024 sz | s |||| 0|eng d 9783031595677 978-3-031-59567-7 10.1007/978-3-031-59567-7 doi QD241-441 PNN bicssc SCI013040 bisacsh PNN thema Progress in the Chemistry of Organic Natural Products 124 [electronic resource] / edited by A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Yoshinori Asakawa, Ji-Kai Liu, Verena M. Dirsch. 1st ed. 2024. Cham : Springer Nature Switzerland : Imprint: Springer, 2024. VII, 233 p. 157 illus., 77 illus. in color. online resource. text txt rdacontent computer c rdamedia online resource cr rdacarrier text file PDF rda Progress in the Chemistry of Organic Natural Products, 2192-4309 ; 124 Chapter 1: Natural Products Dereplication: Databases and Analytical Methods by Perez Victoria -- Chapter 2: The Chemical Ecology of Plant Natural Products by Li et al -- Chapter 3: Chemical Constituents Isolated from the Lichen Biome of Selected Species Native to North America by Rakotondraibe and Spjut. This volume presents three chapters discussing a range of topics. Chapter 1 deals with the development of efficient methods for compound dereplication that have been critical in the re-emergence of research on natural products as a source of new drug leads. It describes the main methods of dereplication, which rely on the combined use of large natural product databases and spectral libraries, alongside the information obtained from chromatographic, UV-Vis, MS, and NMR spectroscopic analyses of the samples of interest. Chapter 2 describes 989 plant natural products and their ecological functions in plant-herbivore, plant-microorganism, and plant-plant interactions. These compounds include alkaloids, phenols, terpenoids, and other structural types. The information presented should provide the basis for in-depth research on these plant natural products and their natural functions, and also for their further development and utilization. Chapter 3 focuses on lichens, with each constituting a symbiotic association composed of a primary mycobiont and one or more photobionts living mutualistically. Covered are lichens and their bionts, taxonomic identification, and their chemical constituents as exemplified by what is found in lichen biomes, especially those endemic to North America. Extraction and isolation procedures, as well as updates on dereplication methods using mass spectrometric GNPS and NMR spectroscopic spin network fingerprint procedures, and marker-based techniques to identify lichens are discussed. The isolation and structure elucidation of secondary metabolites of an endolichenic Penicillium species that produces bioactive compounds is described in detail. Natural products. Plant ecology. Analytical chemistry. Chemistry, Organic. 65325 Natural Products. Plant Ecology. Analytical Chemistry. Bioanalytical Chemistry. 84826 Organic Chemistry. 65327 Kinghorn, A. Douglas. editor. (orcid)0000-0002-6647-8707 https://orcid.org/0000-0002-6647-8707 edt http://id.loc.gov/vocabulary/relators/edt 72463 Falk, Heinz. editor. edt http://id.loc.gov/vocabulary/relators/edt 72464 Gibbons, Simon. editor. (orcid)0000-0003-1587-6809 https://orcid.org/0000-0003-1587-6809 edt http://id.loc.gov/vocabulary/relators/edt 72465 Asakawa, Yoshinori. editor. (orcid)0000-0002-1847-412X https://orcid.org/0000-0002-1847-412X edt http://id.loc.gov/vocabulary/relators/edt 72466 Liu, Ji-Kai. editor. (orcid)0000-0001-6279-7893 https://orcid.org/0000-0001-6279-7893 edt http://id.loc.gov/vocabulary/relators/edt 72467 Dirsch, Verena M. editor. (orcid)0000-0002-9261-5293 https://orcid.org/0000-0002-9261-5293 edt http://id.loc.gov/vocabulary/relators/edt 72468 SpringerLink (Online service) Springer Nature eBook Printed edition: 9783031595660 Printed edition: 9783031595684 Printed edition: 9783031595691 Progress in the Chemistry of Organic Natural Products, 2192-4309 ; 124 72469 https://doi.org/10.1007/978-3-031-59567-7 ZDB-2-CMS ZDB-2-SXC 63623 63623