04220nam a22004215i 4500001001800000003000900018005001700027007001500044008004100059020001800100024003500118050001600153072001600169072002300185072001500208245022400223250001800447264007500465300006500540336002600605337002600631338003600657347002400693505102300717520149401740650001603234650001603250700008103266700008003347700007903427700007803506710003403584773002603618776003603644776003603680776003603716856004603752978-3-031-63557-1DE-He21320251030113142.0cr nn 008mamaa241015s2024    sz |    s    |||| 0|eng d  a97830316355717 a10.1007/978-3-031-63557-12doi 4aRC666-701.2 7aMJD2bicssc 7aMED0100002bisacsh 7aMJD2thema10aSimulation in Cardiovascular Critical Care Medicineh[electronic resource] :bIntegration of Pathophysiology, Monitoring, and Therapy /cedited by Ronald A. Bronicki, Sebastian C. Tume, Daniel Burkhoff, Daniel J. Penny.  a1st ed. 2024. 1aCham :bSpringer International Publishing :bImprint: Springer,c2024.  aXIV, 174 p. 98 illus., 97 illus. in color.bonline resource.  atextbtxt2rdacontent  acomputerbc2rdamedia  aonline resourcebcr2rdacarrier  atext filebPDF2rda0 aChapter 1: Introduction on CV physiology and pathophysiology using the ventricular pressure volume relation and time varying elastance model -- Chapter 2: Review of hemodynamic monitoring & vasoactive agents -- Chatper 3: Simulation generated clinical vignette on cardiogenic shock -- Chapter 4: Simulation generated clinical vignette on mechanical circulatory support -- Chapter 5: Simulation generated clinical vignetted on cardiomyopathies -- Chapter 6: Review of ventricular response to a volume load followed by simulation generated clinical vignettes on aortic and mitral regurgitations (acute, chronic compensated and chronic decompensated states) -- Chapter 7: Review of ventricular response to a pressure load followed by simulation generated clinical vignettes on systemic & pulmonary hypertension and aortic stenosis (acute, chronic compensated and decompensated states) -- Chapter 8: Heart Lung interactions: underlying principles and simulation generated vignettes on diastolic and systolic heart failure.  aThis book uses a validated cardiovascular simulator to illustrate cardiovascular physiology and pathophysiology, principles of hemodynamic monitoring, and the impact of therapy in patients with a wide spectrum of critical care diseases. The simulator considers the closed-loop nature of the cardiovascular system and is thus ideally suited for demonstrating the complex and dynamic nature of the cardiovascular system. The book uses the Harvi cardiovascular simulator (Harvi Dynamics, Inc) in which heart chambers are modeled according to the time-varying elastance principles of Suga and Sunagawa, and Guyton’s model of the vasculature, which describes systemic and pulmonary vascular properties by a series of resistances and capacitances. The simulator generates ventricular pressure-volume loops from each of the four chambers, time-dependent tracings of pressure, flow and volumes, and the hemodynamic parameters derived from these signals. The principles of the time varying elastance model are reviewed and then applied to a spectrum of cardiovascular lesions, including acute and chronic systolic heart failure, sepsis phenotypes, pulmonary hypertension, valvular disease, and the impact of therapies such as vasoactive agents and acute and chronic mechanical circulatory support devices. Simulation in Cardiovascular Critical Care Medicine is a valuable resource for all levels of learners in the fields of Cardiology, Critical Care Medicine, and Cardiac Critical Care Medicine. 0aCardiology.14aCardiology.1 aBronicki, Ronald A.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt1 aTume, Sebastian C.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt1 aBurkhoff, Daniel.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt1 aPenny, Daniel J.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt2 aSpringerLink (Online service)0 tSpringer Nature eBook08iPrinted edition:z978303163556408iPrinted edition:z978303163558808iPrinted edition:z978303163559540uhttps://doi.org/10.1007/978-3-031-63557-1