Marti, Marcelo A. editor. edt http://id.loc.gov/vocabulary/relators/edt Turjanski, Adrian Gustavo. editor. edt http://id.loc.gov/vocabulary/relators/edt Fernández Do Porto, Dario. editor. edt http://id.loc.gov/vocabulary/relators/edt SpringerLink (Online service) text sz 2024 1st ed. 2024. monographic eng

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electronic resource

access IX, 256 p. 80 illus., 70 illus. in color. online resource. This volume focuses on target-oriented approximations to drug discovery, including target selection, binding pocket detection, and current uses and variants of molecular dynamics and molecular docking. The primary audience is PhD and graduates working in the field of molecular biology, structural biology, pharmaceutical sciences. Prioritizing Drug Targets in Pathogenic Bacteria by Harnessing Structural Biology, Metabolic Analysis, and Omics Data Integration -- Regulatory small RNAs as antimicrobial drug targets -- Riboswitches as antimicrobial targets -- Pre-selection of compounds for lead identification in virtual screening campaigns -- Docking and Bias Docking -- Molecular Dynamics and its Significance in Drug Discovery -- Deep Learning Strategies for Enhanced Molecular Docking and Virtual Screening -- Integrating computational approaches from non-synonymous sequence variations to molecular structure for drug repositioning targeting the SARS-CoV-2 Spike protein. edited by Marcelo A. Marti, Adrian Gustavo Turjanski, Dario Fernández Do Porto. Medicine Research Biology Research Pharmacology Drugs Design Pharmaceutical chemistry Pharmacy Biomedical Research Pharmacology Structure-Based Drug Design Pharmaceutics Pharmacy R850.A1-854 QH315-320 9783031691621 https://doi.org/10.1007/978-3-031-69162-1 https://doi.org/10.1007/978-3-031-69162-1 241015 20251030113143.0 978-3-031-69162-1