04333nam a22005415i 4500001001800000003000900018005001700027007001500044008004100059020003700100024003500137050001200172072001700184072001600201072002300217072001500240245020200255250001800457264007200475300006400547336002600611337002600637338003600663347002400699505114700723520116201870650003403032650002103066650002103087650002503108650002203133650002503155650003303180650003403213650003103247700008703278700008303365700008403448710003403532773002603566776003603592776003603628776003603664856004603700912001403746912001403760999001703774978-981-97-4723-8DE-He21320251030113228.0cr nn 008mamaa241015s2024 si | s |||| 0|eng d a97898197472389978-981-97-4723-87 a10.1007/978-981-97-4723-82doi 4aRB112.5 7aMBGR2bicssc 7aPSB2bicssc 7aMED0080002bisacsh 7aPNB2thema10aClinical Applications of Biomolecules in Disease Diagnosish[electronic resource] :bA Comprehensive Guide to Biochemistry and Metabolism /cedited by Ram Lakhan Singh, Pankaj Singh, Neelam Pathak. a1st ed. 2024. 1aSingapore :bSpringer Nature Singapore :bImprint: Springer,c2024. aXX, 448 p. 74 illus., 57 illus. in color.bonline resource. atextbtxt2rdacontent acomputerbc2rdamedia aonline resourcebcr2rdacarrier atext filebPDF2rda0 aChapter 1_Introduction to Clinical Applications of Biomolecules in Disease Diagnosis -- Chapter 2_Carbohydrate Metabolism in Health and Diseases -- Chapter 3_Protein Metabolism and Its Profiling for the Diagnosis of Metabolic Disorders -- Chapter 4_Disorders of Lipid Metabolism -- Chapter 5_Nucleic Acid Metabolism and Disorders -- Chapter 6_Vitamins and its Impact on Human Health -- Chapter 7_Electrolytes and Acid-Base Disorders -- Chapter 8_Metabolism of Macro Elements (Calcium, Magnesium, Sodium, Potassium, Chloride and Phosphorus) and Associated disorders -- Chapter 9_Metabolism of Essential Trace Elements and its Disorders -- Chapter 10_Enzymes and their Clinical Applications -- Chapter 11_Hormonal Manifestations of Endocrine Diseases -- Chapter 12_Biomolecules of Blood in Health and Their Role in Health and Diseases -- Chapter 13_Free Radicals and their relation to Diseases and Protection against them -- Chapter 14_Clinical Biochemistry of Cancer -- Chapter 15_Outbreak of Deadly Coronavirus (COVID-19) Pandemic: Diagnosis and Management -- Chapter 16_Techniques for the Identification and Characterization of Biomolecules. aThis textbook introduces the clinical applications of biomolecules in disease diagnosis, covering a range of topics in biochemistry. The book discusses carbohydrate and protein metabolism abnormalities, lipid digestion and absorption defects, disorders of purine and pyrimidine metabolism, and the chemistry and biological roles of water- and fat-soluble vitamins. It also covers the roles of different macroelements and essential trace elements in physiological processes and the prevention of chronic diseases. The final chapter focuses on recent developments in our understanding of the role of enzymes in disease development and diagnosis. The book chapter also explores the causes and effects of free radicals in the body, including oxidative stress and diseases such as cardiovascular and neurodegenerative diseases. Finally, the chapter discusses cancer development, causes, diagnosis methods, biomarkers, and current treatments such as targeted drug therapy, chemotherapy, and radiation therapy. This book is a useful resource for undergraduate and postgraduate students, researchers and practitioners in biochemistry, medicine, and health sciences. 0aClinical biochemistry.967825 0aCytology.967436 0aDiseases.968840 0aBiochemistry.965465 0aMetabolism.92468 0aCell biology.96744014aMedical Biochemistry.96782824aMechanisms of Disease.98182424aMetabolic Pathways.9710951 aSingh, Ram Lakhan.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt9860851 aSingh, Pankaj.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt9860861 aPathak, Neelam.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt9860872 aSpringerLink (Online service)0 tSpringer Nature eBook08iPrinted edition:z978981974722108iPrinted edition:z978981974724508iPrinted edition:z978981974725240uhttps://doi.org/10.1007/978-981-97-4723-8 aZDB-2-SME aZDB-2-SXM c64229d64229