05491nam a22006255i 4500 978-3-031-65944-7 DE-He213 20251030113229.0 cr nn 008mamaa 241016s2024 sz | s |||| 0|eng d 9783031659447 978-3-031-65944-7 10.1007/978-3-031-65944-7 doi QR180-189.5 MJCM bicssc MED044000 bisacsh MJCM thema Monocytes and Macrophages in Development, Regeneration, and Disease [electronic resource] / edited by Malgorzata Kloc, Jacek Z. Kubiak, Marta Halasa. 1st ed. 2024. Cham : Springer Nature Switzerland : Imprint: Springer, 2024. VIII, 385 p. 45 illus., 44 illus. in color. online resource. text txt rdacontent computer c rdamedia online resource cr rdacarrier text file PDF rda Results and Problems in Cell Differentiation, 1861-0412 ; 74 Part I Nonimmunologic and Immunologic Functions of Monocytes/Macrophages -- Chapter 1 Homeostatic Functions of Tissue-Resident Macrophages and Their Role in Tissue Maintenance -- Chapter 2 Macrophages and the Extracellular Matrix -- Chapter 3 Immunometabolic Rewiring: A Tale of Macronutrients and Macrophages -- Chapter 4 Macrophage Cell Cycle -- Part II Tissue/Organ Specific Functions of Macrophages -- Chapter 5 Origin and Role of Testicular Macrophages in Testis Development, Steroidogenesis, and Spermatogenesis -- Chapter 6 Adipose Tissue Macrophages -- Chapter 7. Liver Macrophage Diversity in Health and Disease -- Part III Macrophage Functions and Dysfunction in Diseases -- Chapter 8 Crosstalk Between Macrophages and Breast Cancer Cells: Networking Within Tumors -- Chapter 9 Macrophage Dysfunction in Respiratory Disease -- Chapter 10 Macrophages in Lung Repair and Fibrosis -- Chapter 11 Macrophage Polarization and Its Impact on Osteoporosis -- Chapter 12 Unlocking Macrophage Secrets: Histone Deacetylases in Chronic Transplant Rejection -- Chapter 13 Monocytes/Macrophages in Helminth Infections: Key Players in Host Defence, Inflammation, and Tissue Repair -- Chapter 14 Macrophages, Metabolism, Mitochondria, Circadian Rhythmicity and the Pathogen: the Multidimensional Nature of Tuberculosis -- Chapter 15 Role of Monocyte/Macrophages in the Pathogenesis of NeuroHIV. The study and therapeutic application of macrophages is a rapidly developing field. Tremendous progress has been made in understanding the phenotypes and functions of macrophages in healthy and diseased tissues and organs. Following the great success of Volume 62: "Macrophages - Origin, Functions and Biointervention" published in this series, this new book now focuses on the role of monocytes and macrophages in development, regeneration and disease. This new volume offers an overview of the latest developments in monocyte and macrophage subtypes and functions across various tissues including adipose tissue, bones, liver, lungs, testes, and the nervous system. The book also reviews existing and potential therapies targeted towards the macrophages and describes their homeostatic functions. It explores how macrophage cell cycle, metabolism, mitochondrial activity, histone acetylation status, and interaction with the extracellular matrix contribute to changes in macrophage phenotype and function in health and disease. Additionally, it examines the interactions between macrophages and cancer cells, bacteria, helminth parasites, and their role in the colonization and spread of HIV. For ease of reference, the volume is divided into three sections: Part I Nonimmunologic and immunologic functions of monocytes/macrophages Part II Tissue/organ specific functions of macrophages Part III Macrophage functions and dysfunction in diseases This book will be of interest to researchers working in the fields of developmental biology, immunology, cancer research, and therapeutic applications. It is written to inform and inspire experts and newcomers to the field of macrophages. Immunology. 69214 Developmental biology. 67434 Medical microbiology. 63858 Cancer. 4311 Biomaterials. Immunology. 69214 Developmental Biology and Stem Cells. 67438 Medical Microbiology. 63858 Cancer Biology. 67829 Biomaterials. Kloc, Malgorzata. editor. edt http://id.loc.gov/vocabulary/relators/edt 67441 Kubiak, Jacek Z. editor. edt http://id.loc.gov/vocabulary/relators/edt 83876 Halasa, Marta. editor. edt http://id.loc.gov/vocabulary/relators/edt 83877 SpringerLink (Online service) Springer Nature eBook Printed edition: 9783031659430 Printed edition: 9783031659454 Printed edition: 9783031659461 Results and Problems in Cell Differentiation, 1861-0412 ; 74 67443 https://doi.org/10.1007/978-3-031-65944-7 ZDB-2-SBL ZDB-2-SXB 64239 64239