03405nam a22004815i 4500001001800000003000900018005001700027007001500044008004100059020001800100024003500118050001200153072001600165072002300181072001500204245015100219250001800370264007200388300006600460336002600526337002600552338003600578347002400614505075200638520105801390650001602448650002302464650001402487650002202501650001702523650001602540650002302556650001302579650002302592650001702615700007702632710003402709773002602743776003602769776003602805776003602841856004602877978-981-97-1639-5DE-He21320251030113303.0cr nn 008mamaa241108s2024    si |    s    |||| 0|eng d  a97898197163957 a10.1007/978-981-97-1639-52doi 4aRJ1-570 7aMJW2bicssc 7aMED0690002bisacsh 7aMKD2thema10aChildren with Differences in Sex Developmenth[electronic resource] :bTaking a Multidisciplinary Management Approach /cedited by Simmi K. Ratan.  a1st ed. 2024. 1aSingapore :bSpringer Nature Singapore :bImprint: Springer,c2024.  aXV, 793 p. 162 illus., 147 illus. in color.bonline resource.  atextbtxt2rdacontent  acomputerbc2rdamedia  aonline resourcebcr2rdacarrier  atext filebPDF2rda0 aAnatomical differentiation and development of gonads -- Molecular regulation of sexual differentiation -- Hormonal regulation during gonadal development -- rain imprinting during gonadal differentiation -- Gender identity and role -- Gender dysphoria in DSD children -- Metaanalysis and current literature on gender identity disorders -- Psychopathological and psychiatric co-morbidities ingender dysphoria -- Legal aspects of DSD Indian & International scenario -- E volution and history of landmark judgements for DSD -- Terminology and clinical evaluation in the Diagnosis of DSD -- Cytogenetic and Molecular Genetic investigations in DSD -- Imaging and Endoscopy in the Diagnosis of DSD -- Endocrine profiling in diagnosis -- Pathology of DSD.  aThis manual covers all possible aspects of managing a child with differences in sex development, an entity easily missed by the unsuspecting clinician. Managing such children is challenging due to various processes (genetic, hormonal, environmental, chromosomal, and environmental) involved in developing gonads and brain imprinting. The entity of Gender dysphoria adds further to this complexity. With a global uproar caused by the cropping up of medicolegal issues concerning sex allotment and sex of rearing, a need is felt to know about the line of approach to address the problems of management of these children, which does not stop at medical and surgical treatment. Whereas many social and legal organizations are relentlessly working for the cause of such children, there is a lack of comprehensive literature on the round management of such children, which makes the book more of an essential addition to the existing reading material. Esteemed writers give all these aspects and explain lucidly with the help of tables, figures, and diagrams. 0aPediatrics. 0aChildrenxSurgery. 0aHormones. 0aMedical genetics. 0aChromosomes.14aPediatrics.24aPediatric Surgery.24aHormone.24aClinical Genetics.24aChromosomes.1 aRatan, Simmi K.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt2 aSpringerLink (Online service)0 tSpringer Nature eBook08iPrinted edition:z978981971638808iPrinted edition:z978981971640108iPrinted edition:z978981971641840uhttps://doi.org/10.1007/978-981-97-1639-5