02881nam a22005175i 4500 978-3-031-75682-5 DE-He213 20251030113306.0 cr nn 008mamaa 241110s2024 sz | s |||| 0|eng d 9783031756825 978-3-031-75682-5 10.1007/978-3-031-75682-5 doi RS199.5 TCB bicssc SCI010000 bisacsh TCB thema De, Surya K. author. aut http://id.loc.gov/vocabulary/relators/aut 87302 Drug Design and Discovery [electronic resource] : Inhibitors of Mitogen-Activated Protein Kinases / by Surya K. De. 1st ed. 2024. Cham : Springer Nature Switzerland : Imprint: Springer, 2024. XVIII, 196 p. 214 illus., 67 illus. in color. online resource. text txt rdacontent computer c rdamedia online resource cr rdacarrier text file PDF rda Chapter 1: Overview of Protein Kinase inhibitors -- Chapter 2: Biological Roles of MAP kinases -- Chapter 3: ATP-competitive inhibitors -- Chapter 4: ATP-noncompetitive inhibitors and Bi-dentate inhibitors -- Chapter 5: Covalent inhibitors. This book covers the important role small molecules can play in the modulation of stress-activated protein kinase (SAPK), also called the mitogen-activated protein kinase (MAPK) pathway, and the potential this may offer in enabling the development of future medicine therapies. It is clear that MAP kinase pathway therapies could continue to drive increasing interest in the field, both within academic laboratories and also in the biotechnology and pharmaceutical sectors. This book provides an overview of protein kinase inhibitors, the biological roles of MAP kinases, ATP-competitive and non-competitive inhibitors, covalent inhibitors, and more. This book is intended for professors in academia, researchers in pharmaceutical and biotechnology sectors working on protein kinases, and graduate students in pharmacy/chemistry. Drug delivery systems. Pharmacology. 67844 Pharmacy. 64666 Drug Delivery. 69429 Pharmacology. 67844 Pharmacy. 64666 SpringerLink (Online service) Springer Nature eBook Printed edition: 9783031756818 Printed edition: 9783031756832 Printed edition: 9783031756849 https://doi.org/10.1007/978-3-031-75682-5 ZDB-2-SBL ZDB-2-SXB 64852 64852