02662nam a22004695i 4500001001800000003000900018005001700027007001500044008004100059020003700100024003500137050001200172072001600184072002300200072001500223100008100238245012300319250001800442264006900460300006800529336002600597337002600623338003600649347002400685505024500709520083400954650002701788650002501815650002101840650002601861650002501887650002101912710003401933773002601967776003601993776003602029776003602065856004602101912001402147912001402161999001702175978-3-031-75682-5DE-He21320251030113306.0cr nn 008mamaa241110s2024    sz |    s    |||| 0|eng d  a97830317568259978-3-031-75682-57 a10.1007/978-3-031-75682-52doi 4aRS199.5 7aTCB2bicssc 7aSCI0100002bisacsh 7aTCB2thema1 aDe, Surya K.eauthor.4aut4http://id.loc.gov/vocabulary/relators/aut98730210aDrug Design and Discoveryh[electronic resource] :bInhibitors of Mitogen-Activated Protein Kinases /cby Surya K. De.  a1st ed. 2024. 1aCham :bSpringer Nature Switzerland :bImprint: Springer,c2024.  aXVIII, 196 p. 214 illus., 67 illus. in color.bonline resource.  atextbtxt2rdacontent  acomputerbc2rdamedia  aonline resourcebcr2rdacarrier  atext filebPDF2rda0 aChapter 1: Overview of Protein Kinase inhibitors -- Chapter 2: Biological Roles of MAP kinases -- Chapter 3: ATP-competitive inhibitors -- Chapter 4: ATP-noncompetitive inhibitors and Bi-dentate inhibitors -- Chapter 5: Covalent inhibitors.  aThis book covers the important role small molecules can play in the modulation of stress-activated protein kinase (SAPK), also called the mitogen-activated protein kinase (MAPK) pathway, and the potential this may offer in enabling the development of future medicine therapies. It is clear that MAP kinase pathway therapies could continue to drive increasing interest in the field, both within academic laboratories and also in the biotechnology and pharmaceutical sectors. This book provides an overview of protein kinase inhibitors, the biological roles of MAP kinases, ATP-competitive and non-competitive inhibitors, covalent inhibitors, and more. This book is intended for professors in academia, researchers in pharmaceutical and biotechnology sectors working on protein kinases, and graduate students in pharmacy/chemistry. 0aDrug delivery systems. 0aPharmacology.967844 0aPharmacy.96466614aDrug Delivery.96942924aPharmacology.96784424aPharmacy.9646662 aSpringerLink (Online service)0 tSpringer Nature eBook08iPrinted edition:z978303175681808iPrinted edition:z978303175683208iPrinted edition:z978303175684940uhttps://doi.org/10.1007/978-3-031-75682-5  aZDB-2-SBL  aZDB-2-SXB  c64852d64852