03253nam a22004815i 4500001001800000003000900018005001700027007001500044008004100059020001800100024003500118050001600153072001700169072002300186072001600209245011600225250001800341264007200359300006400431336002600495337002600521338003600547347002400583490007000607505068200677520083801359650001602197650001902213650002402232650002302256650001602279650001902295650002502314700007302339700007502412710003402487773002602521776003602547776003602583776003602619830007002655856004602725978-981-97-7288-9DE-He21320251030113316.0cr nn 008mamaa241116s2024    si |    s    |||| 0|eng d  a97898197728897 a10.1007/978-981-97-7288-92doi 4aQR180-189.5 7aMJCM2bicssc 7aMED0440002bisacsh 7aMJCM2thema10aUbiquitination in Immune System and Immune Responseh[electronic resource] /cedited by Hongbo Hu, Xianghui Fu.  a1st ed. 2024. 1aSingapore :bSpringer Nature Singapore :bImprint: Springer,c2024.  aIX, 159 p. 27 illus., 26 illus. in color.bonline resource.  atextbtxt2rdacontent  acomputerbc2rdamedia  aonline resourcebcr2rdacarrier  atext filebPDF2rda1 aAdvances in Experimental Medicine and Biology,x2214-8019 ;v14660 aChapter 1. Decoding Ubiquitin Modifications by Mass Spectrometry -- Chapter 2. Ubiquitination in the T Cell metabolism-based Immunotherapy in Diseases -- Chapter 3. Ubiquitination of Immune System and Cancer Therapy -- Chapter 4. Ubiquitination and Metabolic Disease -- Chapter 5. The Cullin-RING Ligase Family in Immune Regulation -- Chapter 6. The Immune Modulatory Role of TIF1 Proteins -- Chapter 7. Role of Ubiquitin Signaling in Modulating Dendritic Cell Function -- Chapter 8. Ubiquitin Signaling in the Immune System -- Chapter 9. Regulation of the Inflammasome Activation by Ubiquitination Machinery -- Chapter 10. The Function of Ubiquitination In T-Cell Development.  aUbiquitination is a major protein post-translational modification, which is involved in many aspects of cellular procedure. The functions of ubiquitination in immune system and immune response have been intensively studied. This book aims to introduce the latest and crucial achievements, along with the fundamental principles of ubiquitination and immune responses. It covers the proteomic aspects of ubiquitination, the function of ubiquitin in innate and adoptive immunity, the development of immune cells, and the metabolism. The active researchers in this field are invited to contribute the chapters. This book is suitable for graduate students, researchers and readers who are interested in this field. It will provide readers with comprehensive insight into how ubiquitination functions in different aspects of immune system. 0aImmunology. 0aLife sciences. 0aMedicinexResearch. 0aBiologyxResearch.14aImmunology.24aLife Sciences.24aBiomedical Research.1 aHu, Hongbo.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt1 aFu, Xianghui.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt2 aSpringerLink (Online service)0 tSpringer Nature eBook08iPrinted edition:z978981977287208iPrinted edition:z978981977289608iPrinted edition:z9789819772902 0aAdvances in Experimental Medicine and Biology,x2214-8019 ;v146640uhttps://doi.org/10.1007/978-981-97-7288-9