04385nam a22006015i 4500001001800000003000900018005001700027007001500044008004100059020003700100024003500137050001900172050001400191072001600205072002300221072001600244245012300260250001800383264006900401300006400470336002600534337002600560338003600586347002400622490005800646505083200704520140401536650001802940650002602958650002502984650002703009650002303036650002303059650003103082650002503113650002503138650002703163650002303190650003903213650003203252700008903284700008603373710003403459773002603493776003603519776003603555776003603591830006503627856004603692912001403738912001403752999001703766978-3-031-68807-2DE-He21320251030113316.0cr nn 008mamaa241117s2024    sz |    s    |||| 0|eng d  a97830316880729978-3-031-68807-27 a10.1007/978-3-031-68807-22doi 4aTA418.95-455.2 4aQP620-625 7aTGM2bicssc 7aTEC0210002bisacsh 7aTGML2thema10aNucleic Acid Photophysics and Photochemistryh[electronic resource] /cedited by Spiridoula Matsika, Andrew H. Marcus.  a1st ed. 2024. 1aCham :bSpringer Nature Switzerland :bImprint: Springer,c2024.  aIX, 209 p. 82 illus., 75 illus. in color.bonline resource.  atextbtxt2rdacontent  acomputerbc2rdamedia  aonline resourcebcr2rdacarrier  atext filebPDF2rda1 aNucleic Acids and Molecular Biology,x1869-2486 ;v360 aChapter 1. Computational Studies of the Photophysics and Photochemistry of Nucleic Acid Constituents -- Chapter 2. Computational Studies on Photoinduced Charge Transfer Processes in Nucleic Acids: From Watson-Crick Dimers to Quadruple Helices -- Chapter 3. The Photodynamics of Thionated Pyrimidine Nucleobases: Using Time-Resolved Photoelectron Spectroscopy to Explore Characteristics of Excited State Topographies -- Chapter 4. Nucleobases as Molecular Fossils of Prebiotic Photoselection -- Chapter 5. Excited State Dynamics in Silver-DNA Assemblies -- Chapter 6. Fluorescence-Detected Circular Dichroism Spectroscopy for Analysis of Nucleic Acids: A Practical Guide and Review -- Chapter 7. Spectroscopic Approaches for Studies of Site-Specific DNA Base and Backbone ‘Breathing’ Using Exciton-Coupled Dimer-Labeled DNA.  aThis volume focuses on recent advancements in our current understanding of nucleic acid photochemistry and its relationship to biologically relevant phenomena. Understanding the photophysical properties of nucleic acids is an area of longstanding and active research. Over the years, the field has greatly benefitted from steady advances in spectroscopic techniques and computational methods to study molecular excited states, which have facilitated detailed studies of the behavior of nucleic acids and their components after they absorb light. Experiments performed on ultrafast time scales (femtoseconds - picoseconds) have permitted the accurate determination of excited state lifetimes, while computational studies have provided detailed microscopic information about the mechanisms involved. As our understanding of the fundamental photophysics of nucleic acids has advanced, current studies now focus on systems of higher complexity, and introduce novel optical techniques to investigate the interactions between nucleic acids and proteins. Spectroscopic studies of nucleic acids, particularly nucleic acid constructs labeled with optical probes, can yield richly detailed information important to molecular biology, biochemistry and biophysics. This book is a must-read for anyone interested in the photophysical properties of nucleic acids and their role in biologically relevant phenomena. 0aBiomaterials. 0aNucleic acids.970554 0aBiochemistry.965465 0aPhotochemistry.974202 0aMolecular biology. 0aBiophysics.966239 0aBiologyxTechnique.96784514aNucleic Acid.97055724aBiochemistry.96546524aPhotochemistry.97420224aMolecular Biology.24aSingle-Molecule Biophysics.97245224aBiophysical Methods.9761111 aMatsika, Spiridoula.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt9876431 aMarcus, Andrew H.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt9876442 aSpringerLink (Online service)0 tSpringer Nature eBook08iPrinted edition:z978303168806508iPrinted edition:z978303168808908iPrinted edition:z9783031688096 0aNucleic Acids and Molecular Biology,x1869-2486 ;v3698764540uhttps://doi.org/10.1007/978-3-031-68807-2  aZDB-2-SBL  aZDB-2-SXB  c65013d65013