04845nam a22005535i 4500001001800000003000900018005001700027007001500044008004100059020001800100024003500118050001400153072001600167072002300183072001500206245012200221250001800343264006900361300006700430336002600497337002600523338003600549347002400585490012200609505107900731520170101810650001103511650001403522650001803536650002603554650001603580650001403596650001603610650001103626650002603637650002303663650001803686650001603704700007903720700007803799700007803877710003403955773002603989776003604015776003604051776003604087830012204123856004604245978-3-031-64853-3DE-He21320251030113323.0cr nn 008mamaa241123s2024 sz | s |||| 0|eng d a97830316485337 a10.1007/978-3-031-64853-32doi 4aQK600-638 7aPSQ2bicssc 7aSCI0940002bisacsh 7aPSQ2thema10aHuman and Animal Relationshipsh[electronic resource] /cedited by Axel A. Brakhage, Olaf Kniemeyer, Peter F. Zipfel. a3rd ed. 2024. 1aCham :bSpringer Nature Switzerland :bImprint: Springer,c2024. aXVIII, 275 p. 38 illus., 36 illus. in color.bonline resource. atextbtxt2rdacontent acomputerbc2rdamedia aonline resourcebcr2rdacarrier atext filebPDF2rda1 aThe Mycota, A Comprehensive Treatise on Fungi as Experimental Systems for Basic and Applied Research,x2945-8056 ;v60 aPart I. Pathogens -- Chapter 1. Trinity of Environment, Animals, and Humans: A Résumé in the Case of the Fungal Order Mucorales -- Chapter 2. Pathogenicity Strategies of Candida Species During Interaction with Epithelial Cells -- Chapter 3. Malassezia Yeasts in Animals in the Next-Generation Sequencing Era -- Chapter 4. Extracellular Proteins and Their Roles in Aspergillus Fumigatus Pathogenesis -- Part II. Host-Pathogen Interaction -- Chapter 5. RNA as a Mediator of Host-Fungal Pathogenesis -- Chapter 6. The Human Gut Mycobiome and Its Potential as a Regulator of the Host’s Metabolic Health -- Chapter 7. The Host Innate Immune Response to Pathogenic Candida Albicans and Other Fungal Pathogens -- Chapter 8. Mammalian Pattern Recognition Receptors (Prrs) Involved in Recognition of Fungi -- Chapter 9. Infection Models for Human Pathogenic Fungi -- Part III. Techniques -- Chapter 10. Transcriptomic Analyses of Host Colonisation in Fungal Pathogens of Humans -- Chapter 11. Proteomics and Its Application to the Human-Pathogenic Fungus Aspergillus Fumigatus. aEstimates based on sequencing data suggest that there are around 5.1 million species of fungi. Yet only a small number of fungi are harmful to animals, including humans. In addition to host-pathogen interactions, there are also mutualistic interactions between fungi and animals. Diseases caused by pathogenic fungi range from allergic reactions and superficial infections to invasive mycoses, and have a significant impact on human and animal life. Fungi are also cultivated by animals as a food source in highly developed relationships or are even involved in gut mutualism. This 3rd edition of Volume 6 of The Mycota highlights exemplary interactions between fungal pathogens and their host(s). The book is organized in three parts: Part 1 summarizes our current understanding of important pathogenic fungi such as Candida species, Malassezia yeasts, Aspergillus fumigatus and fungi of the order Mucorales. Part 2 addresses the characterization of the host response towards pathogenic fungi. It focuses on RNA as a mediator of host-pathogen interactions, the human gut mycobiome, the role of the innate immune system in fighting infections, pattern recognition receptors involved in fungal infections, and a summary of established infection models for studying host-fungal-pathogen interactions. Part 3 provides insights into the impact transcriptomics and proteomics technologies have on the research of human-pathogenic fungi. The up-to-date reviews by experts in the field provide the reader with a comprehensive overview of the various research topics in the field of human and animal relationships with fungi and will hopefully help researchers to find inspiration for their own research. 0aFungi. 0aMycology. 0aMicrobiology. 0aMedical microbiology. 0aPhysiology. 0aCytology. 0aImmunology.14aFungi.24aMedical Microbiology.24aAnimal Physiology.24aCell Biology.24aImmunology.1 aBrakhage, Axel A.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt1 aKniemeyer, Olaf.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt1 aZipfel, Peter F.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt2 aSpringerLink (Online service)0 tSpringer Nature eBook08iPrinted edition:z978303164852608iPrinted edition:z978303164854008iPrinted edition:z9783031648557 0aThe Mycota, A Comprehensive Treatise on Fungi as Experimental Systems for Basic and Applied Research,x2945-8056 ;v640uhttps://doi.org/10.1007/978-3-031-64853-3