04064nam a22005655i 4500 978-3-031-69188-1 DE-He213 20251030114546.0 cr nn 008mamaa 241127s2024 sz | s |||| 0|eng d 9783031691881 978-3-031-69188-1 10.1007/978-3-031-69188-1 doi RC321-580 PSAN bicssc SCI089000 bisacsh PSAN thema Systems Neuroscience [electronic resource] / edited by Albert Cheung-Hoi Yu, Kai Gao, Jiangshan Zhan. 2nd ed. 2024. Cham : Springer Nature Switzerland : Imprint: Springer, 2024. XII, 256 p. 16 illus., 12 illus. in color. online resource. text txt rdacontent computer c rdamedia online resource cr rdacarrier text file PDF rda Advances in Neurobiology, 2190-5223 ; 41 Section A: Principle and Molecular Foundations -- Determination of neuronal activity and its meaning for the processes of learning and memory -- Emergence of the hippocampus as a vector for goal-directed spatial navigation -- Modelling and controlling system dynamics of the brain: an intersection of machine learning and control theory -- Section B: Cutting-Edge Technologies -- Adeno-associated virus mediated gene delivery across the blood-brain barrier -- Virus-based neural circuit tracing -- Spatial omics: navigating neuroscience research into the new era -- Section C: Application and Clinical Practice -- Alzheimer's disease from modeling to mechanism research -- Inflammatory demyelinating diseases of the central nervous system -- Multi-layer analysis of RNA sequencing data in alzheimer’s disease to unravel molecular mysteries -- Opportunities for system neuroscience. The new edition of this popular book brings together experts in the field of Systems Neuroscience to present an overview of the area. Topics covered include how different neural circuits analyze sensory information, form perceptions of the external world, make decisions, and execute movements; how nerve cells behave when connected together to form neural networks; the relationship between molecular and cellular approaches to understanding brain structure and function; the study of high-level mental functions; and studying brain pathologies and disease. Among the topics covered in the new edition are artificial intelligence-assisted computational neuroscience for deciphering neural networks, spatial transcriptomics single cell sequencing, and exome/whole genome sequencing for understanding brain disorders in human genetics. The best way to study the brain, the most complex organ in the body composed of 100 billion neurons with trillions of interconnections, is with a systems biology approach. Neurosciences. 68384 Neural networks (Neurobiology). 79376 Bioinformatics. 64050 Neuroscience. 68386 Systems Neuroscience. 79377 Computational and Systems Biology. 65974 Yu, Albert Cheung-Hoi. editor. edt http://id.loc.gov/vocabulary/relators/edt 88089 Gao, Kai. editor. edt http://id.loc.gov/vocabulary/relators/edt 88090 Zhan, Jiangshan. editor. edt http://id.loc.gov/vocabulary/relators/edt 88091 SpringerLink (Online service) Springer Nature eBook Printed edition: 9783031691874 Printed edition: 9783031691898 Printed edition: 9783031691904 Advances in Neurobiology, 2190-5223 ; 41 72663 https://doi.org/10.1007/978-3-031-69188-1 ZDB-2-SBL ZDB-2-SXB 65234 65234