04024nam a22005415i 4500001001800000003000900018005001700027007001500044008004100059020001800100024003500118050001200153072001700165072002300182072001600205245015100221250001800372264007200390300006400462336002600526337002600552338003600578347002400614505103900638520109901677650002302776650002202799650001202821650001802833650001402851650001802865650002402883650002002907650002302927650002702950650001402977650001802991650002303009700007603032700008203108700007803190710003403268773002603302776003603328776003603364776003603400856004603436978-981-97-4612-5DE-He21320251030114548.0cr nn 008mamaa241127s2024    si |    s    |||| 0|eng d  a97898197461257 a10.1007/978-981-97-4612-52doi 4aRC270.8 7aMJCL2bicssc 7aMED0620002bisacsh 7aMJCL2thema10aProstate Cancer: Molecular Events and Therapeutic Modalitiesh[electronic resource] /cedited by Gautam Sethi, Milad Ashrafizadeh, Nasim Ebrahimi.  a1st ed. 2024. 1aSingapore :bSpringer Nature Singapore :bImprint: Springer,c2024.  aIX, 291 p. 23 illus., 16 illus. in color.bonline resource.  atextbtxt2rdacontent  acomputerbc2rdamedia  aonline resourcebcr2rdacarrier  atext filebPDF2rda0 aChapter 1. Anatomy and function of prostate -- Chapter 2. Epidemiology, risk factors and histopathological profile of prostate cancer -- Chapter 3. Prostate cancer and Inflammation -- Chapter 4. Prostate cancer, apoptosis, autophagy and ferroptosis: Cell death mechanisms and their crosstalk -- Chapter 5. Prostate cancer and metastasis: An emphasis on EMT mechanism -- Chapter 6. Prostate cancer and Wnt/STAT3 signaling -- Chapter 7. Prostate cancer and EZH2 signaling -- Chapter 8. Prostate cancer and PTEN/PI3K/Akt/mTOR signaling -- Chapter 9. Prostate cancer and non-coding RNAs: A focus on miRNAs, lncRNAs and circRNAs -- Chapter 10. Prostate cancer and tumor microenvironment -- Chapter 11. Chemoresistance, radioresistance and androgen-deprivation therapy resistance in prostate cancer -- Chapter 12. Plant derived-natural products in treatment of prostate cancer -- Chapter 13. Gene therapy as a new emerging strategy for prostate cancer -- Chapter 14. Nanoparticle-based therapeutic strategies in prostate cancer suppression.  aThe book covers the various cell signaling pathways responsible for prostate cancer progression, conventional therapies used for prostate cancer treatment, new emerging therapeutics, and challenges in the treatment of cancer patients. It describes the different molecular pathways responsible for prostate cancer progression to improve readers' knowledge about the role of signaling networks, and cellular and molecular aspects of prostate cancer progression. These topics include mechanisms responsible for prostate cancer malignancy with a focus on molecular pathways. It also discusses the current challenges in prostate cancer treatment such as drug resistance and immune evasion and introduces novel therapeutics such as gene therapy and nanotherapeutics for prostate cancer. This book is completely novel and unique and covers all aspects of prostate cancer progression and challenges in therapy while presenting solutions. Written by prestigious researchers around the world, this book will be interesting to researchers and practitioners, especially those working in urological cancers. 0aCancerxTreatment. 0aMedical genetics. 0aCancer. 0aNanomedicine. 0aOncology. 0aEpidemiology. 0aGeneticsxResearch.14aCancer Therapy.24aClinical Genetics.24aCancer Nanotechnology.24aOncology.24aEpidemiology.24aGenetics Research.1 aSethi, Gautam.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt1 aAshrafizadeh, Milad.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt1 aEbrahimi, Nasim.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt2 aSpringerLink (Online service)0 tSpringer Nature eBook08iPrinted edition:z978981974611808iPrinted edition:z978981974613208iPrinted edition:z978981974614940uhttps://doi.org/10.1007/978-981-97-4612-5