03900nam a22004695i 4500001001800000003000900018005001700027007001500044008004100059020003700100024003500137050001400172072001600186072002300202072001500225245009700240250001800337264007200355300006400427336002600491337002600517338003600543347002400579505143200603520080702035650002302842650002202865650002302887650002202910700007902932700008303011700007703094710003403171773002603205776003603231776003603267776003603303856004603339912001403385912001403399999001703413978-981-97-5730-5DE-He21320251030114616.0cr nn 008mamaa241213s2024    si |    s    |||| 0|eng d  a97898197573059978-981-97-5730-57 a10.1007/978-981-97-5730-52doi 4aQL951-991 7aPSC2bicssc 7aSCI0720002bisacsh 7aPSC2thema10aFetal Origin of Diseasesh[electronic resource] /cedited by Hui Wang, Liaobin Chen, Dan Xu.  a1st ed. 2024. 1aSingapore :bSpringer Nature Singapore :bImprint: Springer,c2024.  aXVI, 330 p. 47 illus., 4 illus. in color.bonline resource.  atextbtxt2rdacontent  acomputerbc2rdamedia  aonline resourcebcr2rdacarrier  atext filebPDF2rda0 aChapter 1. Prenatal Adverse Environment and Susceptibility to Fetal-originated Disease -- Chapter 2. Molecular Mechanism of Fetal Developmental Toxicity -- Chapter 3. Epigenetic Mechanism of Fetal-originated Disease -- Chapter 4. Neuroendocrine Programming Mechanism of Fetal-originated Disease -- Chapter 5. Glucocorticoids Programming Mechanism of Fetal-originated Disease -- Chapter 6. Gut Microbiota Mechanism of Fetal-originated Disease -- Chapter 7. Sex Difference of Fetal-originated Disease -- Chapter 8. Multigenerational Genetic Effect of Fetal-originated Disease -- Chapter 9. Developmental Toxicity of Caffeine and Related Fetal-originated Disease -- Chapter 10. Developmental Toxicity of Dexamethasone and Related Fetal-originated Disease -- Chapter 11. Fetal Origin of Metabolic Syndrome -- Chapter 12. Fetal Origin of Diabetes -- Chapter 13. Fetal Origin of Non-alcoholic Fatty Liver Disease -- Chapter 14. Fetal Origin of Hypercholesterolemia -- Chapter 15. Fetal Origin of Osteoporosis -- Chapter 16. Fetal Origin of Osteoarthritis -- Chapter 17. Fetal Origin of Glomerulosclerosis -- Chapter 18. Fetal Origin of Epilepsy -- Chapter 19. Fetal Origin of Testicular Dysplasia -- Chapter 20. Fetal Origin of Premature Ovarian Insufficiency -- Chapter 21. Methods of In vivo and In vitro Study of Fetal-originated Disease -- Chapter 22. Targets for Early Warning and Drug Intervention for Fetal-originated Disease.  aThis book covers two decades of the author’s studies about fetal-originated diseases. It contains researches from the aspects of multiple inducing factors of fetal-originated diseases, such as prenatal xenobiotic exposure, nutritional deficiency and other adverse environment during pregnancy; the establishment of animal models of diseases such as a variety of metabolic and neuropsychiatric diseases; the mechanisms for developmental toxicity and susceptibility to multiple diseases, such as glucocorticoid programming; the identification of series of biomarkers of developmental toxicity; and early warning and prevention and treatment strategies of fetal-originated diseases. The content of this book is systematic and complete. It can provide useful information for researchers of related areas. 0aEmbryology.973447 0aMetabolism.9246814aEmbryology.97344724aMetabolism.924681 aWang, Hui.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt9777461 aChen, Liaobin.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt9888721 aXu, Dan.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt9888732 aSpringerLink (Online service)0 tSpringer Nature eBook08iPrinted edition:z978981975729908iPrinted edition:z978981975731208iPrinted edition:z978981975732940uhttps://doi.org/10.1007/978-981-97-5730-5  aZDB-2-SBL  aZDB-2-SXB  c65685d65685