04144nam a22005055i 4500001001800000003000900018005001700027007001500044008004100059020001800100024003500118050001600153072001500169072001600184072002300200072001400223072001500237245007800252250001800330264007200348300006700420336002600487337002600513338003600539347002400575505109000599520140801689650002403097650001303121650002203134650002903156650002303185650002703208650002503235650003503260650002903295650002503324700007503349710003403424773002603458776003603484776003603520776003603556856004603592978-981-97-7459-3DE-He21320251030114621.0cr nn 008mamaa241216s2024    si |    s    |||| 0|eng d  a97898197745937 a10.1007/978-981-97-7459-32doi 4aQH324-324.9 7aPS2bicssc 7aPDN2bicssc 7aSCI0080002bisacsh 7aPS2thema 7aPDN2thema10aAdvances in Metabolomicsh[electronic resource] /cedited by Vijai Singh.  a1st ed. 2024. 1aSingapore :bSpringer Nature Singapore :bImprint: Springer,c2024.  aXVIII, 391 p. 32 illus., 27 illus. in color.bonline resource.  atextbtxt2rdacontent  acomputerbc2rdamedia  aonline resourcebcr2rdacarrier  atext filebPDF2rda0 a1. Current approaches on metabolomics -- 2. Applications of computational and data sciences in metabolomics -- 3. Design of biosynthetic pathway for production of metabolites -- 4. Dissecting Cellular Heterogeneity: Single-Cell Metabolomics for Unmasking Hidden Variations -- 5. Biosensors for Detection of Metabolites -- 6. Unveiling the Molecular Fingerprint: Mass Spectrometry in Metabolomics -- 7. Utilizing HPLC for Efficient Metabolite Purification -- 8. NMR Spectroscopy for Characterisation of Metabolite -- 9. Transcriptional control for metabolite production -- 10. Microfluids in metabolites detection, production, and optimization -- 11. Cell free systems in metabolomics -- 12. Unlocking the Metabolome: A Guide to Genome Editing for Precision Control of Cellular Chemistry -- 13. Production and Fermentation Optimization of Flavour and Fragrance Molecules -- 14. Bioprocessing and Purification of Metabolites -- 15. Scaling Up Nature's Chemistry: A Guide to Industrial Production of Valuable Metabolites -- 16. Regulatory, economic and educational issues in metabolomics.  aThe book delves into metabolomics which is a rapidly growing field that focuses on the study of chemical processes involving metabolites. These metabolites are small molecules that serve as substrates, intermediates, and end products of cellular metabolism. The book covers a wide range of tools and methods to facilitate metabolomics analysis, including modelling, gas chromatography, GC-MS, HPLC, MALDI, nuclear magnetic resonance, and many others. The book introduces metabolomics and then delves into tools and methods used in metabolomics research, followed by genome-scale analysis and fluxomics, which explore the complex metabolic networks within cells. The design of biosynthetic pathways is discussed in detail, highlighting their significance in manipulating cellular metabolism. The book also explores biosensors, chromatography techniques, NMR spectroscopy, transcriptional control of metabolite production, microfluidics, and the role of artificial intelligence and machine learning in metabolomics research. Additionally, it delves into cell-free systems, bioprocess optimization, fermentation technology, and industrial-scale production of metabolites. This book fills a significant gap in the market with comprehensive coverage and inclusion of diverse topics making it a valuable resource for students, researchers, scientists, clinicians, policymakers, and practitioners in the field. 0aBiologyxTechnique. 0aBiology. 0aMolecular probes. 0aArtificial intelligence. 0aMoleculesxModels.14aBiological Techniques.24aBiological Sciences.24aBiological Sensors and Probes.24aArtificial Intelligence.24aMolecular Modelling.1 aSingh, Vijai.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt2 aSpringerLink (Online service)0 tSpringer Nature eBook08iPrinted edition:z978981977458608iPrinted edition:z978981977460908iPrinted edition:z978981977461640uhttps://doi.org/10.1007/978-981-97-7459-3