04555nam a22005175i 4500 978-981-97-7905-5 DE-He213 20251030114630.0 cr nn 008mamaa 241220s2024 si | s |||| 0|eng d 9789819779055 978-981-97-7905-5 10.1007/978-981-97-7905-5 doi QH671 PSF bicssc SCI017000 bisacsh PSF thema Apoptosis and Human Health: Understanding Mechanistic and Therapeutic Potential [electronic resource] / edited by Kuladip Jana. 1st ed. 2024. Singapore : Springer Nature Singapore : Imprint: Springer, 2024. XX, 457 p. 78 illus., 74 illus. in color. online resource. text txt rdacontent computer c rdamedia online resource cr rdacarrier text file PDF rda Chapter 1: Apoptosis: Intricate connections in cell death pathways and disease implications -- Chapter 2: Apoptosis: A Controlled Cell’s Fate -- Chapter 3: Apoptosis: Novel insights into the role of death receptors and caspases in cell fate -- Chapter 4: Apoptosis: Mechanisms and Clinical Implications -- Chapter 5: Apoptosis and Mitochondria: Cell death mechanisms -- Chapter 6: Apoptosis: ER stress and Disease pathology -- Chapter 7: Apoptosis: Oxidative stress and Antioxidants -- Chapter 8: Caspase Independent Apoptosis: New Insights and Current Perspectives -- Chapter 9: Role of Apoptosis in Cancer: Therapeutic targets and strategies -- Chapter 10: Mechanisms of PANoptosis and its implications in cancer progression and treatment -- Chapter 11: Role of Apoptosis in Neurodegeneration: Therapeutic targets and strategies.-b Chapter 12: Role of Apoptosis in Diabetes: Therapeutic targets and strategies -- Chapter 13: Role of Apoptosis in Cardiovascular diseases: Therapeutic targets and strategies -- Chapter 14: Chapter 15: Role of Apoptosis in Parasitic infections: Therapeutic targets and strategies -- Chapter 15: Role of Apoptosis in Viral infections with special reference to Covid 19: Therapeutic targets and strategies -- Chapter 16: Role of Apoptosis in male Infertility: Therapeutic targets and strategies -- Chapter 17: Role of Apoptosis in aging: Therapeutic targets and strategies -- Chapter 18: Apoptosis: Natural product-derived small molecules as Therapeutics -- Chapter 19: Apoptosis-based therapeutics and inhibitors in clinical trials or in preclinical state -- Chapter 20: Apoptosis and cancer immunotherapy: Current mechanisms and emerging strategies. This book comprehensively reviews the recent advancements in apoptosis research and evaluates its therapeutic targets and strategies in controlling various human diseases. The initial chapter presents the molecular components that regulate apoptosis and its importance for pathogenic processes. The subsequent chapters discuss the molecular mechanisms and signaling pathways involved in apoptosis induction and inhibition. The book also examines the role of mitochondria-driven apoptosis and therapeutic strategies for targeting mitochondria-mediated cell death. Further, the book discusses the role of apoptosis in different diseases, including neurodegeneration, cancer, diabetes, cardiovascular diseases, parasitic infections, autoimmune diseases, reproductive disorders, and infertility. Towards the end, the book outlines the recent advances in the field of apoptosis-based therapies and explores some highlights of a very active field of drug development. This book is useful for the researchers involved in designing and developing new drugs and drug targets for the treatment of different human diseases. Cell death. Diseases. 68840 Cytology. 67436 Cell Death. Diseases. 68840 Cell Biology. 67440 Jana, Kuladip. editor. edt http://id.loc.gov/vocabulary/relators/edt 89285 SpringerLink (Online service) Springer Nature eBook Printed edition: 9789819779048 Printed edition: 9789819779062 Printed edition: 9789819779079 https://doi.org/10.1007/978-981-97-7905-5 ZDB-2-SME ZDB-2-SXM 65901 65901