03405nam a22004575i 4500001001800000003000900018005001700027007001500044008004100059020003700100024003500137050001300172050001000185072001600195072002300211072001500234100008200249245011500331250001800446264007200464300006600536336002600602337002600628338003600654347002400690505072800714520110101442650002802543650002502571650004802596650004402644710003402688773002602722776003602748776003602784776003602820856004602856912001402902912001402916999001702930978-981-97-6512-6DE-He21320251030114632.0cr nn 008mamaa241220s2024    si |    s    |||| 0|eng d  a97898197651269978-981-97-6512-67 a10.1007/978-981-97-6512-62doi 4aR856-857 4aQH513 7aMQW2bicssc 7aTEC0590002bisacsh 7aMQW2thema1 aWang, Guixue.eauthor.4aut4http://id.loc.gov/vocabulary/relators/aut98933614aThe Mechanobiology in Atherosclerosish[electronic resource] :bBasic, Frontier and Advance /cby Guixue Wang.  a1st ed. 2024. 1aSingapore :bSpringer Nature Singapore :bImprint: Springer,c2024.  aXXI, 232 p. 121 illus., 84 illus. in color.bonline resource.  atextbtxt2rdacontent  acomputerbc2rdamedia  aonline resourcebcr2rdacarrier  atext filebPDF2rda0 aLipid Concentration Polarization and Atherosclerosis -- Low Shear Stress Regulates Biological Behavior of Vascular Endothelial Cells to Promote Atherosclerosis -- Hypothesis of Hemodynamics for Vascular Endothelial Cell Injury Repair -- Mechanobiological Mechanism of Cardiovascular and Cerebrovascular Development -- Mechanobiological Mechanisms of Atherosclerotic Plaque Formation -- Mechanobiological Mechanism by Which Id1 Regulates Lipid Absorption in Atherosclerotic Plaque Formation -- Mechanical Mechanisms of In-Stent Restenosis and Atherosclerosis following the Implantation of Intravascular Stents -- Mechanobiology Mechanism for the Inhibitory Effect of Vascular Restenosis by Drug Regulation of Cell Viability.  aThis book is based on prior research conducted by the author's team, integrating the latest advancements in biomechanics and mechanobiology related to atherosclerosis from both domestic and international peers. It explores the mechanobiological mechanisms and prevention strategies for atherosclerosis and intravascular stent restenosis. The topics covered include: lipoprotein concentration polarization, stress response of vascular endothelial cells, biomechanical mechanisms in cardiovascular and cerebrovascular development, atherosclerotic plaque formation, in-stent restenosis, and post-stent implantation atherosclerosis. Additionally, the book presents the mechanobiological mechanisms of drug regulation for cell viability and inhibition of vascular restenosis, as well as the latest frontiers and advancements in these areas. It carries significant reference value for postgraduates and young researchers in cardiovascular physiology and pathology, particularly those involved in biomedical engineering, basic medicine, and clinical medicine focused on atherosclerotic disease research. 0aBiomedical engineering. 0aBiomechanics.96677714aBiomechanical Analysis and Modeling.96677824aBiomedical Devices and Instrumentation.2 aSpringerLink (Online service)0 tSpringer Nature eBook08iPrinted edition:z978981976511908iPrinted edition:z978981976513308iPrinted edition:z978981976514040uhttps://doi.org/10.1007/978-981-97-6512-6  aZDB-2-SME  aZDB-2-SXM  c65925d65925