03641nam a22005175i 4500001001800000003000900018005001700027007001500044008004100059020003700100024003500137050001400172072001700186072002300203072001600226245016000242250001800402264007200420300006500492336002600557337002600583338003600609347002400645505066300669520110201332650002602434650003702460650002802497650002002525650002302545650002502568650003502593650003402628650002302662700008202685700009702767710003402864773002602898776003602924776003602960776003602996856004603032912001403078912001403092999001703106978-981-97-6822-6DE-He21320251030114639.0cr nn 008mamaa241225s2024    si |    s    |||| 0|eng d  a97898197682269978-981-97-6822-67 a10.1007/978-981-97-6822-62doi 4aRC321-580 7aPSAN2bicssc 7aSCI0890002bisacsh 7aPSAN2thema10aEnzymes in Neurodegenerative Disordersh[electronic resource] :bMechanism and Therapeutic Potentials /cedited by Bijo Mathew, Della Grace Thomas Parambi.  a1st ed. 2024. 1aSingapore :bSpringer Nature Singapore :bImprint: Springer,c2024.  aXII, 189 p. 32 illus., 30 illus. in color.bonline resource.  atextbtxt2rdacontent  acomputerbc2rdamedia  aonline resourcebcr2rdacarrier  atext filebPDF2rda0 aChapter 1. Introduction of enzymes in neurodegenerative disorders -- Chapter 2. Role of enzymes in Alzheimer’s disease -- Chapter 3. Role of enzymes in amyotrophic lateral sclerosis -- Chapter 4. Enzymes involved in multiple sclerosis -- Chapter 5. Role of enzymes in epilepsy -- Chapter 6. Role of enzymes in Huntington’s disease -- Chapter 7. Role of enzymes in Parkinson's disease -- Chapter 8. Role of enzymes in Prion disease: Molecular mechanism -- Chapter 9. Modulation of several downstream cascades served by enzymes in the pathogenesis of stroke -- Chapter 10. Future directions and challenges in enzyme research for neurodegenerative diseases.  aThis book delves into the correlation between different enzymes and neurodegenerative disorders. It investigates the intricate processes that contribute to the decline of cognitive functions, memory impairment, and other incapacitating symptoms of Alzheimer's disease. The book examines the roles of diverse enzymes in Amyotrophic Lateral Sclerosis and their effects on the motor neurons, leading to muscle weakness, paralysis, and eventual fatality. Moreover, it examines the association between depression and the enzymes responsible, providing a fresh viewpoint on the biochemical foundation of this ailment. Lastly, the book explores the connection between enzymes and Parkinson's disease, discussing the mechanisms that cause the death of dopamine-producing neurons and the related symptoms. By examining the functions of various enzymes in Parkinson's disease, the book presents a distinct outlook on the intricate interplay between enzymes and several neurological conditions, imparting readers with a comprehensive understanding of the fundamental mechanisms that underlie these disorders. 0aNeurosciences.968384 0aNervous systemxDiseases.964036 0aNeurophysiology.973730 0aNeurons.973731 0aEnzymology.97363014aNeuroscience.96838624aNeurological Disorders.97404224aCellular Neuroscience.97373324aEnzymology.9736301 aMathew, Bijo.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt9895781 aParambi, Della Grace Thomas.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt9895792 aSpringerLink (Online service)0 tSpringer Nature eBook08iPrinted edition:z978981976821908iPrinted edition:z978981976823308iPrinted edition:z978981976824040uhttps://doi.org/10.1007/978-981-97-6822-6  aZDB-2-SBL  aZDB-2-SXB  c66039d66039