03838nam a22005055i 4500001001800000003000900018005001700027007001500044008004100059020003700100024003500137050001300172050001300185072001500198072001500213072002300228072001400251072001400265245009400279250001800373264007200391300006600463336002600529337002600555338003600581347002400617505105200641520107301693650002302766650003602789650002302825650003502848650002302883700008502906700008202991710003403073773002603107776003603133776003603169776003603205856004603241912001403287912001403301999001703315978-981-97-8410-3DE-He21320251030114918.0cr nn 008mamaa250102s2024    si |    s    |||| 0|eng d  a97898197841039978-981-97-8410-37 a10.1007/978-981-97-8410-32doi 4aRC1-1245 4aRC1-1245 7aMJ2bicssc 7aMJ2bicssc 7aMED0450002bisacsh 7aMJ2thema 7aMJ2thema10aIrritable Bowel Syndromeh[electronic resource] /cedited by Takeshi Kamiya, Shin Fukudo.  a1st ed. 2024. 1aSingapore :bSpringer Nature Singapore :bImprint: Springer,c2024.  aVIII, 208 p. 27 illus., 17 illus. in color.bonline resource.  atextbtxt2rdacontent  acomputerbc2rdamedia  aonline resourcebcr2rdacarrier  atext filebPDF2rda0 aDefinition of irritable bowel syndrome -- The epidemiology of irritable bowel syndrome -- Part II. Pathophysiology -- Neurogastroenterology - Brain-Gut Axis, Stress and Psychological Factors -- Neuro-gastroenterology - Neurotransmitter, endocrine substance and motility -- Role of microbiota in the pathophysiology of irritable bowel syndrome -- Mucosal inflammation and visceral hypersensitivity in irritable bowel syndrome -- Genetic factors -- Part III. Diagnosis -- Diagnostic algorithm for IBS -- Differential diagnosis -- Comorbiditie -- Part IV. Treatment -- Pharmacotherapy for IBS-D -- Pharmacotherapy for irritable bowel syndrome with constipation -- GI motility modifier, bulking polymer and Herbal medicine -- Antidepressant, anxiolytics and psychotherapy -- Diet and behavioral modification for irritable bowel syndrome -- Probiotics and antibiotics -- Part V. Recent special topics -- Fecal Microbiota Transplantation for Treatment of Irritable Bowel Syndrome -- Clinical study design and evaluation of the efficacy in the treatment.  aThis edited book brings together 5 general themes of irritable bowel syndrome (IBS), presenting the latest information on the epidemiology, pathophysiology, diagnosis, treatment and a number of current topics. IBS is a functional bowel disorder associated with chromic abdominal pain and altered bowel habits without identifiable organic etiology, however, to date there is no known, agreed-upon disease mechanism. This book offers insights into the various factors potentially contributing to the symptoms, and provides data on the various globally recognized strategies, including novel pharmacological treatment agents. It also discusses geographical differences and region-specific factors such as medical systems, life styles, dietary habits, gut microbiota, social stress, and genetics. The book promotes further exploration of the disease by offering a comprehensive bibliography for each chapter. It is a valuable and thought-provoking resource for clinicians, researchers, residents and PIs who are interested in the latest basic and clinical research on IBS. 0aInternal medicine. 0aMedicine, Psychosomatic.97519814aInternal Medicine.24aPsychosomatic Medicine.97520024aInternal Medicine.1 aKamiya, Takeshi.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt9900901 aFukudo, Shin.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt9900912 aSpringerLink (Online service)0 tSpringer Nature eBook08iPrinted edition:z978981978409708iPrinted edition:z978981978411008iPrinted edition:z978981978412740uhttps://doi.org/10.1007/978-981-97-8410-3  aZDB-2-SME  aZDB-2-SXM  c66306d66306