03989nam a22004935i 4500001001800000003000900018005001700027007001500044008004100059020003700100024003500137050001400172072001700186072002300203072001600226245015700242250001800399264006900417300006500486336002600551337002600577338003600603347002400639505082900663520133801492650002102830650003002851650002002881650002102901650003002922650002002952700009302972700008603065700008503151710003403236773002603270776003603296776003603332776003603368856004603404912001403450912001403464999001703478978-3-031-76746-3DE-He21320251030114931.0cr nn 008mamaa250126s2024    sz |    s    |||| 0|eng d  a97830317674639978-3-031-76746-37 a10.1007/978-3-031-76746-32doi 4aRC254-282 7aMJCL2bicssc 7aMED0620002bisacsh 7aMJCL2thema10aGallbladder Cancerh[electronic resource] :bA Comprehensive Guide to Management /cedited by Mauro Monteiro Correia, Michael A. Choti, Flavio G. Rocha.  a1st ed. 2024. 1aCham :bSpringer Nature Switzerland :bImprint: Springer,c2024.  aXII, 206 p. 45 illus., 24 illus. in color.bonline resource.  atextbtxt2rdacontent  acomputerbc2rdamedia  aonline resourcebcr2rdacarrier  atext filebPDF2rda0 aAnatomy and embryology of the intra and extrahepatic biliary tract -- Exploring anatomy, macroscopic and microscopic structures and physiological functions of the gallbladder -- Gallbladder cancer epidemiology and risk factors -- Is there a role for prophylactic cholecystectomy? -- Pre-malignant lesions of the gallbladder -- Pathology features of GBC -- Imaging of GBC -- Staging for GBC -- Indication of Reoperation in Incidental Gallbladder Cancer -- Management of incidentally diagnosed GBC at the time of cholecystectomy -- Management of incidental GBC diagnosed after gallbladder surgery -- Surgical results for open, laparoscopic and robotic resections for GBC -- GBC : Surgical results of an oncologic center -- Chemotherapy for GBC -- Role of ctDNA in the management of GBC -- Molecularly targeted therapy for GBC.  aGallbladder Cancer: A Comprehensive Guide to Management was planned as a thorough, yet objective text about gallbladder cancer, encompassing from epidemiology and pathogenesis to the present cutting edge technology and ongoing research. This work provides a comprehensive review of a worldwide scope disease as a collaboration of renowned researchers from different continents, including the latest discussions of crucial topics on gallbladder cancer management. The epidemiology content covers epidemiologic data, trends over time, risk factors, incidence and cancer specific mortality rates. Chapters describe the intrinsic molecular mechanisms of oncogenesis associated with the pathogenetic mechanisms, genomics, proteomics and transcriptomics. Regarding prevention, prophylactic measures and preventive use of drugs is presented. Chapters also describe the clinical, radiological, laboratorial aspects of the different forms of gallbladder cancer. In addition, the role of biomarkers for diagnosis, prognosis and follow up is explored. Readers will also find topics such as management through multidisciplinary treatment, surgical controversies, systemic therapy and radiation therapy. The book is a valuable resource to general and cancer surgeons, HPB surgeons, clinical oncologists, gastroenterologists and medical residents. 0aOncology.970760 0aInterventional radiology. 0aSurgery.97208014aOncology.97076024aInterventional Radiology.24aSurgery.9720801 aCorreia, Mauro Monteiro.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt9904561 aChoti, Michael A.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt9904571 aRocha, Flavio G.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt9904582 aSpringerLink (Online service)0 tSpringer Nature eBook08iPrinted edition:z978303176745608iPrinted edition:z978303176747008iPrinted edition:z978303176748740uhttps://doi.org/10.1007/978-3-031-76746-3  aZDB-2-SME  aZDB-2-SXM  c66522d66522