03586nam a22005295i 4500 978-3-031-77171-2 DE-He213 20251030114932.0 cr nn 008mamaa 250126s2024 sz | s |||| 0|eng d 9783031771712 978-3-031-77171-2 10.1007/978-3-031-77171-2 doi RC346-429.2 MJN bicssc MED056000 bisacsh MKJ thema Triadafilopoulos, George. author. aut http://id.loc.gov/vocabulary/relators/aut 90469 The Gut in Parkinson's Disease [electronic resource] / by George Triadafilopoulos. 1st ed. 2024. Cham : Springer Nature Switzerland : Imprint: Springer, 2024. XIII, 176 p. 81 illus., 71 illus. in color. online resource. text txt rdacontent computer c rdamedia online resource cr rdacarrier text file PDF rda Introduction -- Parkinson’s disease (PD) - Generalities -- Parkinson’s disease (PD) and the gut - Gut PD -- Understanding the essentials of the normal gut movement and sensation -- What to watch for in gut PD: Mouth -- Pharynx and esophagus -- Small intestine -- Small intestinal bacterial overgrowth (SIBO) Colon -- Malnutrition and weight loss in PD -- Diagnostic and Assessment tools in PD -- GI symptom questionnaires in PD. At present, there is minimal and misleading knowledge of gastrointestinal dysfunction in Parkinson's disease among primary neurologists and gastroenterologists. This book reviews our current understanding of the GI involvement in PD, as many experiments suggest that the gut might be the site where the disease starts. Also discussed is how the gut dysfunction causes symptoms from the top (mouth) to the bottom (anal canal), and because of their frequency and severity, they contribute to disease progression and disability. In addition, the book covers the negative effects of small intestinal bacterial overgrowth (SIBO) and of a frequently silent stomach infection by Helicobacter pylori infection on the absorption of antiparkinsonian drugs, in turn causing motor fluctuations and inadequate treatment response. The Gut in Parkinson's Disease serves as a bridge between patients, their movement disorders specialists, and other health care providers who currently provide compartmentalized and at times conflicting care for such needy patients. The book distills the clinical and research experience of the author, who -as a Clinical Professor of Medicine (Gastroenterology) at Stanford University School of Medicine over the past 20 years- managed hundreds of patients with Parkinson’s Disease suffering from gut manifestations. Neurology . 66816 Nervous system Diseases. 64036 Primary care (Medicine). 64645 Patient education. Neurology. 66816 Neurological Disorders. 74042 Primary Care Medicine. 64645 Patient Education. SpringerLink (Online service) Springer Nature eBook Printed edition: 9783031771705 Printed edition: 9783031771729 https://doi.org/10.1007/978-3-031-77171-2 ZDB-2-SME ZDB-2-SXM 66528 66528