04666nam a22005175i 4500001001800000003000900018005001700027007001500044008004100059020003700100024003500137050001400172072001600186072002300202072001500225245012800240250001800368264007200386300006600458336002600524337002600550338003600576347002400612505110700636520169301743650002003436650001803456650002103474650003003495650003203525650002703557650002103584650002703605700008503632700008603717700008603803710003403889773002603923776003603949776003603985776003604021856004604057912001404103912001404117999001704131978-981-96-0301-5DE-He21320251030114935.0cr nn 008mamaa250130s2024    si |    s    |||| 0|eng d  a97898196030159978-981-96-0301-57 a10.1007/978-981-96-0301-52doi 4aQH301-705 7aPSA2bicssc 7aSCI0860002bisacsh 7aPSA2thema10aSmall Molecules for Cancer Treatmenth[electronic resource] /cedited by Surajit Pathak, Antara Banerjee, Asim K. Duttaroy.  a1st ed. 2024. 1aSingapore :bSpringer Nature Singapore :bImprint: Springer,c2024.  aXIII, 269 p. 22 illus., 21 illus. in color.bonline resource.  atextbtxt2rdacontent  acomputerbc2rdamedia  aonline resourcebcr2rdacarrier  atext filebPDF2rda0 a1. Small Molecule Therapeutics targeting Ligand-independent activation of Androgen Receptor in Prostate Cancer -- 2. Small molecule targeted compounds for cancer therapy through different pathways -- 3. Exploring small molecule therapies: A comprehensive study on their efficacy in cancer treatment -- 4. Unvailing The Symphony Of Small Molecules In Cutaneous Harmony, Pathophysiology And Regeneration -- 5. Relevance Of Small Molecule Inhibitors in Advancing Cancer Therapeutics -- 6. Application of artificial intelligence in small molecules in cancer therapy -- 7. Role Of Peptides In Oral Cancer -- 8. Innovative Strategies in Cancer Therapy: Overcoming Challenges through Small Molecule and Peptide Design -- 9. Therapeutic Relevance Of Glycosylation Inhibitors In Cancer -- 10. Developments of aptamer-drug conjugates for targeted cancer therapy -- 11. Natural small molecules and their anti-cancer effects -- 12. Small Molecule Inhibitors: Precision Tools Targeting Oncogenic Pathways for Therapeutic Intervention in Cancer -- 13. Small Molecules And Peptides Targetting Tumour Microenvironment.  aThe book explores role of small molecules and peptides in cancer therapy, with a focus on (Aptamer-drug conjugates, Androgen Receptor and Tyrosine Kinase inhibitors, and Glycosylation inhibitors. Small molecule inhibitors targeting oncogenic pathways such as EGFR and PI3K inhibitors, Peptides in oral cancer such as Antimicrobial peptides, Cell Penetrating Peptides, Tumour targeting peptides, Natural small molecules with anti-cancer effects such as phenolic compounds, alkaloids, terpenoids and steroids, Phthalides and lectins, Peptides targeting the tumor microenvironment such as GM-CSF's, LAG3, PD 1, CCL2, CCR-5, CXCR4 inhibitors). An introductory chapter covers the foundation for understanding their significance in cancer treatment. The book delves into the versatility and precision of small molecules, highlighting their advantages in drug delivery and formulation strategies. It emphasizes the expansion of therapeutic horizons through small molecule peptides, shedding light on their potential in targeting tumor microenvironments and advancing cancer therapeutics. Additionally, the book discusses combination therapies and synergistic effects, offering a deeper understanding of integrating different therapeutic approaches. Furthermore, it addresses emerging trends, challenges, safety considerations, and the relevance of small-molecule inhibitors. This book provides a crucial update on the latest advancements and serves as a valuable resource for researchers, clinicians, and students interested in the rapidly evolving landscape of cancer treatment, offering an overview of the potential and complexities associated with these compounds in the fight against cancer. 0aBiology.968861 0aCancer.94311 0aOncology.970760 0aCancerxTreatment.96372214aBiological Sciences.96886524aCancer Biology.96782924aOncology.97076024aCancer Therapy.9734141 aPathak, Surajit.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt9754241 aBanerjee, Antara.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt9754251 aDuttaroy, Asim K.eeditor.4edt4http://id.loc.gov/vocabulary/relators/edt9905712 aSpringerLink (Online service)0 tSpringer Nature eBook08iPrinted edition:z978981960300808iPrinted edition:z978981960302208iPrinted edition:z978981960303940uhttps://doi.org/10.1007/978-981-96-0301-5  aZDB-2-SME  aZDB-2-SXM  c66577d66577